How causal inference concepts can guide research into the effects of climate on infectious diseases

Fuente: arXiv
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Main Authors: Guevara, Laura Andrea Barrero, Kramer, Sarah C, Kurth, Tobias, de Cellès, Matthieu Domenech
Format: Preprint
Published: 2024
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author Guevara, Laura Andrea Barrero
Kramer, Sarah C
Kurth, Tobias
de Cellès, Matthieu Domenech
author_facet Guevara, Laura Andrea Barrero
Kramer, Sarah C
Kurth, Tobias
de Cellès, Matthieu Domenech
contents A pressing question resulting from global warming is how infectious diseases will be affected by climate change. Answering this question requires research into the effects of weather on the population dynamics of transmission and infection; elucidating these effects, however, has proven difficult due to the challenges of assessing causality from the predominantly observational data available in epidemiological research. Here, we show how concepts from causal inference -- the sub-field of statistics aiming at inferring causality from data -- can guide that research. Through a series of case studies, we illustrate how such concepts can help assess study design and strategically choose a study's location, evaluate and reduce the risk of bias, and interpret the multifaceted effects of meteorological variables on transmission. More broadly, we argue that interdisciplinary approaches based on explicit causal frameworks are crucial for reliably estimating the effect of weather and accurately predicting the consequences of climate change.
format Preprint
id arxiv_https___arxiv_org_abs_2402_12507
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle How causal inference concepts can guide research into the effects of climate on infectious diseases
Guevara, Laura Andrea Barrero
Kramer, Sarah C
Kurth, Tobias
de Cellès, Matthieu Domenech
Populations and Evolution
Quantitative Methods
A pressing question resulting from global warming is how infectious diseases will be affected by climate change. Answering this question requires research into the effects of weather on the population dynamics of transmission and infection; elucidating these effects, however, has proven difficult due to the challenges of assessing causality from the predominantly observational data available in epidemiological research. Here, we show how concepts from causal inference -- the sub-field of statistics aiming at inferring causality from data -- can guide that research. Through a series of case studies, we illustrate how such concepts can help assess study design and strategically choose a study's location, evaluate and reduce the risk of bias, and interpret the multifaceted effects of meteorological variables on transmission. More broadly, we argue that interdisciplinary approaches based on explicit causal frameworks are crucial for reliably estimating the effect of weather and accurately predicting the consequences of climate change.
title How causal inference concepts can guide research into the effects of climate on infectious diseases
topic Populations and Evolution
Quantitative Methods
url https://arxiv.org/abs/2402.12507