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Main Authors: Li, Jinghang, Santini, Tales, Huang, Yuanzhe, Mettenburg, Joseph M., Ibrahim, Tamer S., Aizenstein, Howard J., Wu, Minjie
Format: Preprint
Published: 2024
Subjects:
Online Access:https://arxiv.org/abs/2402.12701
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author Li, Jinghang
Santini, Tales
Huang, Yuanzhe
Mettenburg, Joseph M.
Ibrahim, Tamer S.
Aizenstein, Howard J.
Wu, Minjie
author_facet Li, Jinghang
Santini, Tales
Huang, Yuanzhe
Mettenburg, Joseph M.
Ibrahim, Tamer S.
Aizenstein, Howard J.
Wu, Minjie
contents White matter hyperintensity (WMH) remains the top imaging biomarker for neurodegenerative diseases. Robust and accurate segmentation of WMH holds paramount significance for neuroimaging studies. The growing shift from 3T to 7T MRI necessitates robust tools for harmonized segmentation across field strengths and artifacts. Recent deep learning models exhibit promise in WMH segmentation but still face challenges, including diverse training data representation and limited analysis of MRI artifacts' impact. To address these, we introduce wmh_seg, a novel deep learning model leveraging a transformer-based encoder from SegFormer. wmh_seg is trained on an unmatched dataset, including 1.5T, 3T, and 7T FLAIR images from various sources, alongside with artificially added MR artifacts. Our approach bridges gaps in training diversity and artifact analysis. Our model demonstrated stable performance across magnetic field strengths, scanner manufacturers, and common MR imaging artifacts. Despite the unique inhomogeneity artifacts on ultra-high field MR images, our model still offers robust and stable segmentation on 7T FLAIR images. Our model, to date, is the first that offers quality white matter lesion segmentation on 7T FLAIR images.
format Preprint
id arxiv_https___arxiv_org_abs_2402_12701
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle wmh_seg: Transformer based U-Net for Robust and Automatic White Matter Hyperintensity Segmentation across 1.5T, 3T and 7T
Li, Jinghang
Santini, Tales
Huang, Yuanzhe
Mettenburg, Joseph M.
Ibrahim, Tamer S.
Aizenstein, Howard J.
Wu, Minjie
Image and Video Processing
Computer Vision and Pattern Recognition
White matter hyperintensity (WMH) remains the top imaging biomarker for neurodegenerative diseases. Robust and accurate segmentation of WMH holds paramount significance for neuroimaging studies. The growing shift from 3T to 7T MRI necessitates robust tools for harmonized segmentation across field strengths and artifacts. Recent deep learning models exhibit promise in WMH segmentation but still face challenges, including diverse training data representation and limited analysis of MRI artifacts' impact. To address these, we introduce wmh_seg, a novel deep learning model leveraging a transformer-based encoder from SegFormer. wmh_seg is trained on an unmatched dataset, including 1.5T, 3T, and 7T FLAIR images from various sources, alongside with artificially added MR artifacts. Our approach bridges gaps in training diversity and artifact analysis. Our model demonstrated stable performance across magnetic field strengths, scanner manufacturers, and common MR imaging artifacts. Despite the unique inhomogeneity artifacts on ultra-high field MR images, our model still offers robust and stable segmentation on 7T FLAIR images. Our model, to date, is the first that offers quality white matter lesion segmentation on 7T FLAIR images.
title wmh_seg: Transformer based U-Net for Robust and Automatic White Matter Hyperintensity Segmentation across 1.5T, 3T and 7T
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2402.12701