Voice-Driven Mortality Prediction in Hospitalized Heart Failure Patients: A Machine Learning Approach Enhanced with Diagnostic Biomarkers

Fuente: arXiv
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Autores principales: Ahmadli, Nihat, Sarsil, Mehmet Ali, Mizrak, Berk, Karauzum, Kurtulus, Shaker, Ata, Tulumen, Erol, Mirzamidinov, Didar, Ural, Dilek, Ergen, Onur
Formato: Preprint
Publicado: 2024
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author Ahmadli, Nihat
Sarsil, Mehmet Ali
Mizrak, Berk
Karauzum, Kurtulus
Shaker, Ata
Tulumen, Erol
Mirzamidinov, Didar
Ural, Dilek
Ergen, Onur
author_facet Ahmadli, Nihat
Sarsil, Mehmet Ali
Mizrak, Berk
Karauzum, Kurtulus
Shaker, Ata
Tulumen, Erol
Mirzamidinov, Didar
Ural, Dilek
Ergen, Onur
contents Addressing heart failure (HF) as a prevalent global health concern poses difficulties in implementing innovative approaches for enhanced patient care. Predicting mortality rates in HF patients, in particular, is difficult yet critical, necessitating individualized care, proactive management, and enabling educated decision-making to enhance outcomes. Recently, the significance of voice biomarkers coupled with Machine Learning (ML) has surged, demonstrating remarkable efficacy, particularly in predicting heart failure. The synergy of voice analysis and ML algorithms provides a non-invasive and easily accessible means to evaluate patients' health. However, there is a lack of voice biomarkers for predicting mortality rates among heart failure patients with standardized speech protocols. Here, we demonstrate a powerful and effective ML model for predicting mortality rates in hospitalized HF patients through the utilization of voice biomarkers. By seamlessly integrating voice biomarkers into routine patient monitoring, this strategy has the potential to improve patient outcomes, optimize resource allocation, and advance patient-centered HF management. In this study, a Machine Learning system, specifically a logistic regression model, is trained to predict patients' 5-year mortality rates using their speech as input. The model performs admirably and consistently, as demonstrated by cross-validation and statistical approaches (p-value < 0.001). Furthermore, integrating NT-proBNP, a diagnostic biomarker in HF, improves the model's predictive accuracy substantially.
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id arxiv_https___arxiv_org_abs_2402_13812
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Voice-Driven Mortality Prediction in Hospitalized Heart Failure Patients: A Machine Learning Approach Enhanced with Diagnostic Biomarkers
Ahmadli, Nihat
Sarsil, Mehmet Ali
Mizrak, Berk
Karauzum, Kurtulus
Shaker, Ata
Tulumen, Erol
Mirzamidinov, Didar
Ural, Dilek
Ergen, Onur
Machine Learning
Sound
Audio and Speech Processing
Addressing heart failure (HF) as a prevalent global health concern poses difficulties in implementing innovative approaches for enhanced patient care. Predicting mortality rates in HF patients, in particular, is difficult yet critical, necessitating individualized care, proactive management, and enabling educated decision-making to enhance outcomes. Recently, the significance of voice biomarkers coupled with Machine Learning (ML) has surged, demonstrating remarkable efficacy, particularly in predicting heart failure. The synergy of voice analysis and ML algorithms provides a non-invasive and easily accessible means to evaluate patients' health. However, there is a lack of voice biomarkers for predicting mortality rates among heart failure patients with standardized speech protocols. Here, we demonstrate a powerful and effective ML model for predicting mortality rates in hospitalized HF patients through the utilization of voice biomarkers. By seamlessly integrating voice biomarkers into routine patient monitoring, this strategy has the potential to improve patient outcomes, optimize resource allocation, and advance patient-centered HF management. In this study, a Machine Learning system, specifically a logistic regression model, is trained to predict patients' 5-year mortality rates using their speech as input. The model performs admirably and consistently, as demonstrated by cross-validation and statistical approaches (p-value < 0.001). Furthermore, integrating NT-proBNP, a diagnostic biomarker in HF, improves the model's predictive accuracy substantially.
title Voice-Driven Mortality Prediction in Hospitalized Heart Failure Patients: A Machine Learning Approach Enhanced with Diagnostic Biomarkers
topic Machine Learning
Sound
Audio and Speech Processing
url https://arxiv.org/abs/2402.13812