Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Preprint |
| Published: |
2024
|
| Subjects: | |
| Online Access: | https://arxiv.org/abs/2402.14080 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1866910665771319296 |
|---|---|
| author | Nolte, Daniel Ghosh, Souparno Pal, Ranadip |
| author_facet | Nolte, Daniel Ghosh, Souparno Pal, Ranadip |
| contents | Deep learning models are being adopted and applied on various critical decision-making tasks, yet they are trained to provide point predictions without providing degrees of confidence. The trustworthiness of deep learning models can be increased if paired with uncertainty estimations. Conformal Prediction has emerged as a promising method to pair machine learning models with prediction intervals, allowing for a view of the model's uncertainty. However, popular uncertainty estimation methods for conformal prediction fail to provide heteroskedastic intervals that are equally accurate for all samples. In this paper, we propose a method to estimate the uncertainty of each sample by calculating the variance obtained from a Deep Regression Forest. We show that the deep regression forest variance improves the efficiency and coverage of normalized inductive conformal prediction on a drug response prediction task. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2402_14080 |
| institution | arXiv |
| publishDate | 2024 |
| record_format | arxiv |
| spellingShingle | Efficient Normalized Conformal Prediction and Uncertainty Quantification for Anti-Cancer Drug Sensitivity Prediction with Deep Regression Forests Nolte, Daniel Ghosh, Souparno Pal, Ranadip Machine Learning Artificial Intelligence Deep learning models are being adopted and applied on various critical decision-making tasks, yet they are trained to provide point predictions without providing degrees of confidence. The trustworthiness of deep learning models can be increased if paired with uncertainty estimations. Conformal Prediction has emerged as a promising method to pair machine learning models with prediction intervals, allowing for a view of the model's uncertainty. However, popular uncertainty estimation methods for conformal prediction fail to provide heteroskedastic intervals that are equally accurate for all samples. In this paper, we propose a method to estimate the uncertainty of each sample by calculating the variance obtained from a Deep Regression Forest. We show that the deep regression forest variance improves the efficiency and coverage of normalized inductive conformal prediction on a drug response prediction task. |
| title | Efficient Normalized Conformal Prediction and Uncertainty Quantification for Anti-Cancer Drug Sensitivity Prediction with Deep Regression Forests |
| topic | Machine Learning Artificial Intelligence |
| url | https://arxiv.org/abs/2402.14080 |