Zero-Shot Pediatric Tuberculosis Detection in Chest X-Rays using Self-Supervised Learning

Fuente: arXiv
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Autores principales: Capellán-Martín, Daniel, Parida, Abhijeet, Gómez-Valverde, Juan J., Sanchez-Jacob, Ramon, Roshanitabrizi, Pooneh, Linguraru, Marius G., Ledesma-Carbayo, María J., Anwar, Syed M.
Formato: Preprint
Publicado: 2024
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author Capellán-Martín, Daniel
Parida, Abhijeet
Gómez-Valverde, Juan J.
Sanchez-Jacob, Ramon
Roshanitabrizi, Pooneh
Linguraru, Marius G.
Ledesma-Carbayo, María J.
Anwar, Syed M.
author_facet Capellán-Martín, Daniel
Parida, Abhijeet
Gómez-Valverde, Juan J.
Sanchez-Jacob, Ramon
Roshanitabrizi, Pooneh
Linguraru, Marius G.
Ledesma-Carbayo, María J.
Anwar, Syed M.
contents Tuberculosis (TB) remains a significant global health challenge, with pediatric cases posing a major concern. The World Health Organization (WHO) advocates for chest X-rays (CXRs) for TB screening. However, visual interpretation by radiologists can be subjective, time-consuming and prone to error, especially in pediatric TB. Artificial intelligence (AI)-driven computer-aided detection (CAD) tools, especially those utilizing deep learning, show promise in enhancing lung disease detection. However, challenges include data scarcity and lack of generalizability. In this context, we propose a novel self-supervised paradigm leveraging Vision Transformers (ViT) for improved TB detection in CXR, enabling zero-shot pediatric TB detection. We demonstrate improvements in TB detection performance ($\sim$12.7% and $\sim$13.4% top AUC/AUPR gains in adults and children, respectively) when conducting self-supervised pre-training when compared to fully-supervised (i.e., non pre-trained) ViT models, achieving top performances of 0.959 AUC and 0.962 AUPR in adult TB detection, and 0.697 AUC and 0.607 AUPR in zero-shot pediatric TB detection. As a result, this work demonstrates that self-supervised learning on adult CXRs effectively extends to challenging downstream tasks such as pediatric TB detection, where data are scarce.
format Preprint
id arxiv_https___arxiv_org_abs_2402_14741
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Zero-Shot Pediatric Tuberculosis Detection in Chest X-Rays using Self-Supervised Learning
Capellán-Martín, Daniel
Parida, Abhijeet
Gómez-Valverde, Juan J.
Sanchez-Jacob, Ramon
Roshanitabrizi, Pooneh
Linguraru, Marius G.
Ledesma-Carbayo, María J.
Anwar, Syed M.
Computer Vision and Pattern Recognition
Image and Video Processing
Tuberculosis (TB) remains a significant global health challenge, with pediatric cases posing a major concern. The World Health Organization (WHO) advocates for chest X-rays (CXRs) for TB screening. However, visual interpretation by radiologists can be subjective, time-consuming and prone to error, especially in pediatric TB. Artificial intelligence (AI)-driven computer-aided detection (CAD) tools, especially those utilizing deep learning, show promise in enhancing lung disease detection. However, challenges include data scarcity and lack of generalizability. In this context, we propose a novel self-supervised paradigm leveraging Vision Transformers (ViT) for improved TB detection in CXR, enabling zero-shot pediatric TB detection. We demonstrate improvements in TB detection performance ($\sim$12.7% and $\sim$13.4% top AUC/AUPR gains in adults and children, respectively) when conducting self-supervised pre-training when compared to fully-supervised (i.e., non pre-trained) ViT models, achieving top performances of 0.959 AUC and 0.962 AUPR in adult TB detection, and 0.697 AUC and 0.607 AUPR in zero-shot pediatric TB detection. As a result, this work demonstrates that self-supervised learning on adult CXRs effectively extends to challenging downstream tasks such as pediatric TB detection, where data are scarce.
title Zero-Shot Pediatric Tuberculosis Detection in Chest X-Rays using Self-Supervised Learning
topic Computer Vision and Pattern Recognition
Image and Video Processing
url https://arxiv.org/abs/2402.14741