Enhance Eye Disease Detection using Learnable Probabilistic Discrete Latents in Machine Learning Architectures

Fuente: arXiv
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Autori principali: Prabhakaran, Anirudh, Xiao, YeKun, Cheng, Ching-Yu, Liu, Dianbo
Natura: Preprint
Pubblicazione: 2024
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author Prabhakaran, Anirudh
Xiao, YeKun
Cheng, Ching-Yu
Liu, Dianbo
author_facet Prabhakaran, Anirudh
Xiao, YeKun
Cheng, Ching-Yu
Liu, Dianbo
contents Ocular diseases, including diabetic retinopathy and glaucoma, present a significant public health challenge due to their high prevalence and potential for causing vision impairment. Early and accurate diagnosis is crucial for effective treatment and management. In recent years, deep learning models have emerged as powerful tools for analysing medical images, such as retina imaging. However, challenges persist in model relibability and uncertainty estimation, which are critical for clinical decision-making. This study leverages the probabilistic framework of Generative Flow Networks (GFlowNets) to learn the posterior distribution over latent discrete dropout masks for the classification and analysis of ocular diseases using fundus images. We develop a robust and generalizable method that utilizes GFlowOut integrated with ResNet18 and ViT models as the backbone in identifying various ocular conditions. This study employs a unique set of dropout masks - none, random, bottomup, and topdown - to enhance model performance in analyzing these fundus images. Our results demonstrate that our learnable probablistic latents significantly improves accuracy, outperforming the traditional dropout approach. We utilize a gradient map calculation method, Grad-CAM, to assess model explainability, observing that the model accurately focuses on critical image regions for predictions. The integration of GFlowOut in neural networks presents a promising advancement in the automated diagnosis of ocular diseases, with implications for improving clinical workflows and patient outcomes.
format Preprint
id arxiv_https___arxiv_org_abs_2402_16865
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Enhance Eye Disease Detection using Learnable Probabilistic Discrete Latents in Machine Learning Architectures
Prabhakaran, Anirudh
Xiao, YeKun
Cheng, Ching-Yu
Liu, Dianbo
Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
Ocular diseases, including diabetic retinopathy and glaucoma, present a significant public health challenge due to their high prevalence and potential for causing vision impairment. Early and accurate diagnosis is crucial for effective treatment and management. In recent years, deep learning models have emerged as powerful tools for analysing medical images, such as retina imaging. However, challenges persist in model relibability and uncertainty estimation, which are critical for clinical decision-making. This study leverages the probabilistic framework of Generative Flow Networks (GFlowNets) to learn the posterior distribution over latent discrete dropout masks for the classification and analysis of ocular diseases using fundus images. We develop a robust and generalizable method that utilizes GFlowOut integrated with ResNet18 and ViT models as the backbone in identifying various ocular conditions. This study employs a unique set of dropout masks - none, random, bottomup, and topdown - to enhance model performance in analyzing these fundus images. Our results demonstrate that our learnable probablistic latents significantly improves accuracy, outperforming the traditional dropout approach. We utilize a gradient map calculation method, Grad-CAM, to assess model explainability, observing that the model accurately focuses on critical image regions for predictions. The integration of GFlowOut in neural networks presents a promising advancement in the automated diagnosis of ocular diseases, with implications for improving clinical workflows and patient outcomes.
title Enhance Eye Disease Detection using Learnable Probabilistic Discrete Latents in Machine Learning Architectures
topic Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2402.16865