Causal Graph ODE: Continuous Treatment Effect Modeling in Multi-agent Dynamical Systems

Fuente: arXiv
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Autori principali: Huang, Zijie, Hwang, Jeehyun, Zhang, Junkai, Baik, Jinwoo, Zhang, Weitong, Wodarz, Dominik, Sun, Yizhou, Gu, Quanquan, Wang, Wei
Natura: Preprint
Pubblicazione: 2024
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author Huang, Zijie
Hwang, Jeehyun
Zhang, Junkai
Baik, Jinwoo
Zhang, Weitong
Wodarz, Dominik
Sun, Yizhou
Gu, Quanquan
Wang, Wei
author_facet Huang, Zijie
Hwang, Jeehyun
Zhang, Junkai
Baik, Jinwoo
Zhang, Weitong
Wodarz, Dominik
Sun, Yizhou
Gu, Quanquan
Wang, Wei
contents Real-world multi-agent systems are often dynamic and continuous, where the agents co-evolve and undergo changes in their trajectories and interactions over time. For example, the COVID-19 transmission in the U.S. can be viewed as a multi-agent system, where states act as agents and daily population movements between them are interactions. Estimating the counterfactual outcomes in such systems enables accurate future predictions and effective decision-making, such as formulating COVID-19 policies. However, existing methods fail to model the continuous dynamic effects of treatments on the outcome, especially when multiple treatments (e.g., "stay-at-home" and "get-vaccine" policies) are applied simultaneously. To tackle this challenge, we propose Causal Graph Ordinary Differential Equations (CAG-ODE), a novel model that captures the continuous interaction among agents using a Graph Neural Network (GNN) as the ODE function. The key innovation of our model is to learn time-dependent representations of treatments and incorporate them into the ODE function, enabling precise predictions of potential outcomes. To mitigate confounding bias, we further propose two domain adversarial learning-based objectives, which enable our model to learn balanced continuous representations that are not affected by treatments or interference. Experiments on two datasets (i.e., COVID-19 and tumor growth) demonstrate the superior performance of our proposed model.
format Preprint
id arxiv_https___arxiv_org_abs_2403_00178
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Causal Graph ODE: Continuous Treatment Effect Modeling in Multi-agent Dynamical Systems
Huang, Zijie
Hwang, Jeehyun
Zhang, Junkai
Baik, Jinwoo
Zhang, Weitong
Wodarz, Dominik
Sun, Yizhou
Gu, Quanquan
Wang, Wei
Machine Learning
Artificial Intelligence
Real-world multi-agent systems are often dynamic and continuous, where the agents co-evolve and undergo changes in their trajectories and interactions over time. For example, the COVID-19 transmission in the U.S. can be viewed as a multi-agent system, where states act as agents and daily population movements between them are interactions. Estimating the counterfactual outcomes in such systems enables accurate future predictions and effective decision-making, such as formulating COVID-19 policies. However, existing methods fail to model the continuous dynamic effects of treatments on the outcome, especially when multiple treatments (e.g., "stay-at-home" and "get-vaccine" policies) are applied simultaneously. To tackle this challenge, we propose Causal Graph Ordinary Differential Equations (CAG-ODE), a novel model that captures the continuous interaction among agents using a Graph Neural Network (GNN) as the ODE function. The key innovation of our model is to learn time-dependent representations of treatments and incorporate them into the ODE function, enabling precise predictions of potential outcomes. To mitigate confounding bias, we further propose two domain adversarial learning-based objectives, which enable our model to learn balanced continuous representations that are not affected by treatments or interference. Experiments on two datasets (i.e., COVID-19 and tumor growth) demonstrate the superior performance of our proposed model.
title Causal Graph ODE: Continuous Treatment Effect Modeling in Multi-agent Dynamical Systems
topic Machine Learning
Artificial Intelligence
url https://arxiv.org/abs/2403.00178