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Main Authors: Chen, Xiaolan, Zhao, Ziwei, Zhang, Weiyi, Xu, Pusheng, Gao, Le, Xu, Mingpu, Wu, Yue, Li, Yinwen, Shi, Danli, He, Mingguang
Format: Preprint
Published: 2024
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Online Access:https://arxiv.org/abs/2403.00840
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author Chen, Xiaolan
Zhao, Ziwei
Zhang, Weiyi
Xu, Pusheng
Gao, Le
Xu, Mingpu
Wu, Yue
Li, Yinwen
Shi, Danli
He, Mingguang
author_facet Chen, Xiaolan
Zhao, Ziwei
Zhang, Weiyi
Xu, Pusheng
Gao, Le
Xu, Mingpu
Wu, Yue
Li, Yinwen
Shi, Danli
He, Mingguang
contents Artificial intelligence (AI) has gained significant attention in healthcare consultation due to its potential to improve clinical workflow and enhance medical communication. However, owing to the complex nature of medical information, large language models (LLM) trained with general world knowledge might not possess the capability to tackle medical-related tasks at an expert level. Here, we introduce EyeGPT, a specialized LLM designed specifically for ophthalmology, using three optimization strategies including role-playing, finetuning, and retrieval-augmented generation. In particular, we proposed a comprehensive evaluation framework that encompasses a diverse dataset, covering various subspecialties of ophthalmology, different users, and diverse inquiry intents. Moreover, we considered multiple evaluation metrics, including accuracy, understandability, trustworthiness, empathy, and the proportion of hallucinations. By assessing the performance of different EyeGPT variants, we identify the most effective one, which exhibits comparable levels of understandability, trustworthiness, and empathy to human ophthalmologists (all Ps>0.05). Overall, ur study provides valuable insights for future research, facilitating comprehensive comparisons and evaluations of different strategies for developing specialized LLMs in ophthalmology. The potential benefits include enhancing the patient experience in eye care and optimizing ophthalmologists' services.
format Preprint
id arxiv_https___arxiv_org_abs_2403_00840
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle EyeGPT: Ophthalmic Assistant with Large Language Models
Chen, Xiaolan
Zhao, Ziwei
Zhang, Weiyi
Xu, Pusheng
Gao, Le
Xu, Mingpu
Wu, Yue
Li, Yinwen
Shi, Danli
He, Mingguang
Computation and Language
Artificial Intelligence
Artificial intelligence (AI) has gained significant attention in healthcare consultation due to its potential to improve clinical workflow and enhance medical communication. However, owing to the complex nature of medical information, large language models (LLM) trained with general world knowledge might not possess the capability to tackle medical-related tasks at an expert level. Here, we introduce EyeGPT, a specialized LLM designed specifically for ophthalmology, using three optimization strategies including role-playing, finetuning, and retrieval-augmented generation. In particular, we proposed a comprehensive evaluation framework that encompasses a diverse dataset, covering various subspecialties of ophthalmology, different users, and diverse inquiry intents. Moreover, we considered multiple evaluation metrics, including accuracy, understandability, trustworthiness, empathy, and the proportion of hallucinations. By assessing the performance of different EyeGPT variants, we identify the most effective one, which exhibits comparable levels of understandability, trustworthiness, and empathy to human ophthalmologists (all Ps>0.05). Overall, ur study provides valuable insights for future research, facilitating comprehensive comparisons and evaluations of different strategies for developing specialized LLMs in ophthalmology. The potential benefits include enhancing the patient experience in eye care and optimizing ophthalmologists' services.
title EyeGPT: Ophthalmic Assistant with Large Language Models
topic Computation and Language
Artificial Intelligence
url https://arxiv.org/abs/2403.00840