Dendrogram of mixing measures: Hierarchical clustering and model selection for finite mixture models

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Hauptverfasser: Do, Dat, Do, Linh, McKinley, Scott A., Terhorst, Jonathan, Nguyen, XuanLong
Format: Preprint
Veröffentlicht: 2024
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author Do, Dat
Do, Linh
McKinley, Scott A.
Terhorst, Jonathan
Nguyen, XuanLong
author_facet Do, Dat
Do, Linh
McKinley, Scott A.
Terhorst, Jonathan
Nguyen, XuanLong
contents We present a new way to summarize and select mixture models via the hierarchical clustering tree (dendrogram) constructed from an overfitted latent mixing measure. Our proposed method bridges agglomerative hierarchical clustering and mixture modeling. The dendrogram's construction is derived from the theory of convergence of the mixing measures, and as a result, we can both consistently select the true number of mixing components and obtain the pointwise optimal convergence rate for parameter estimation from the tree, even when the model parameters are only weakly identifiable. In theory, it explicates the choice of the optimal number of clusters in hierarchical clustering. In practice, the dendrogram reveals more information on the hierarchy of subpopulations compared to traditional ways of summarizing mixture models. Several simulation studies are carried out to support our theory. We also illustrate the methodology with an application to single-cell RNA sequence analysis.
format Preprint
id arxiv_https___arxiv_org_abs_2403_01684
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Dendrogram of mixing measures: Hierarchical clustering and model selection for finite mixture models
Do, Dat
Do, Linh
McKinley, Scott A.
Terhorst, Jonathan
Nguyen, XuanLong
Methodology
Machine Learning
We present a new way to summarize and select mixture models via the hierarchical clustering tree (dendrogram) constructed from an overfitted latent mixing measure. Our proposed method bridges agglomerative hierarchical clustering and mixture modeling. The dendrogram's construction is derived from the theory of convergence of the mixing measures, and as a result, we can both consistently select the true number of mixing components and obtain the pointwise optimal convergence rate for parameter estimation from the tree, even when the model parameters are only weakly identifiable. In theory, it explicates the choice of the optimal number of clusters in hierarchical clustering. In practice, the dendrogram reveals more information on the hierarchy of subpopulations compared to traditional ways of summarizing mixture models. Several simulation studies are carried out to support our theory. We also illustrate the methodology with an application to single-cell RNA sequence analysis.
title Dendrogram of mixing measures: Hierarchical clustering and model selection for finite mixture models
topic Methodology
Machine Learning
url https://arxiv.org/abs/2403.01684