Coronary artery segmentation in non-contrast calcium scoring CT images using deep learning

Fuente: arXiv
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Hauptverfasser: Bujny, Mariusz, Jesionek, Katarzyna, Nalepa, Jakub, Miszalski-Jamka, Karol, Widawka-Żak, Katarzyna, Wolny, Sabina, Kostur, Marcin
Format: Preprint
Veröffentlicht: 2024
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author Bujny, Mariusz
Jesionek, Katarzyna
Nalepa, Jakub
Miszalski-Jamka, Karol
Widawka-Żak, Katarzyna
Wolny, Sabina
Kostur, Marcin
author_facet Bujny, Mariusz
Jesionek, Katarzyna
Nalepa, Jakub
Miszalski-Jamka, Karol
Widawka-Żak, Katarzyna
Wolny, Sabina
Kostur, Marcin
contents Precise localization of coronary arteries in Computed Tomography (CT) scans is critical from the perspective of medical assessment of coronary artery disease. Although various methods exist that offer high-quality segmentation of coronary arteries in cardiac contrast-enhanced CT scans, the potential of less invasive, non-contrast CT in this area is still not fully exploited. Since such fine anatomical structures are hardly visible in this type of medical images, the existing methods are characterized by high recall and low precision, and are used mainly for filtering of atherosclerotic plaques in the context of calcium scoring. In this paper, we address this research gap and introduce a deep learning algorithm for segmenting coronary arteries in multi-vendor ECG-gated non-contrast cardiac CT images which benefits from a novel framework for semi-automatic generation of Ground Truth (GT) via image registration. We hypothesize that the proposed GT generation process is much more efficient in this case than manual segmentation, since it allows for a fast generation of large volumes of diverse data, which leads to well-generalizing models. To investigate and thoroughly evaluate the segmentation quality based on such an approach, we propose a novel method for manual mesh-to-image registration, which is used to create our test-GT. The experimental study shows that the trained model has significantly higher accuracy than the GT used for training, and leads to the Dice and clDice metrics close to the interrater variability.
format Preprint
id arxiv_https___arxiv_org_abs_2403_02544
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Coronary artery segmentation in non-contrast calcium scoring CT images using deep learning
Bujny, Mariusz
Jesionek, Katarzyna
Nalepa, Jakub
Miszalski-Jamka, Karol
Widawka-Żak, Katarzyna
Wolny, Sabina
Kostur, Marcin
Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
Precise localization of coronary arteries in Computed Tomography (CT) scans is critical from the perspective of medical assessment of coronary artery disease. Although various methods exist that offer high-quality segmentation of coronary arteries in cardiac contrast-enhanced CT scans, the potential of less invasive, non-contrast CT in this area is still not fully exploited. Since such fine anatomical structures are hardly visible in this type of medical images, the existing methods are characterized by high recall and low precision, and are used mainly for filtering of atherosclerotic plaques in the context of calcium scoring. In this paper, we address this research gap and introduce a deep learning algorithm for segmenting coronary arteries in multi-vendor ECG-gated non-contrast cardiac CT images which benefits from a novel framework for semi-automatic generation of Ground Truth (GT) via image registration. We hypothesize that the proposed GT generation process is much more efficient in this case than manual segmentation, since it allows for a fast generation of large volumes of diverse data, which leads to well-generalizing models. To investigate and thoroughly evaluate the segmentation quality based on such an approach, we propose a novel method for manual mesh-to-image registration, which is used to create our test-GT. The experimental study shows that the trained model has significantly higher accuracy than the GT used for training, and leads to the Dice and clDice metrics close to the interrater variability.
title Coronary artery segmentation in non-contrast calcium scoring CT images using deep learning
topic Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2403.02544