Convergence of Free Boundaries in the Incompressible Limit of Tumor Growth Models
Fuente:
arXiv
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| Autori principali: | , |
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| Natura: | Preprint |
| Pubblicazione: |
2024
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| _version_ | 1866909133484064768 |
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| author | Tong, Jiajun Zhang, Yuming Paul |
| author_facet | Tong, Jiajun Zhang, Yuming Paul |
| contents | We investigate the general Porous Medium Equations with drift and source terms that model tumor growth. Incompressible limit of such models has been well-studied in the literature, where convergence of the density and pressure variables are established, while it remains unclear whether the free boundaries of the solutions exhibit convergence as well. In this paper, we provide an affirmative result by showing that the free boundaries converge in the Hausdorff distance in the incompressible limit. To achieve this, we quantify the relation between the free boundary motion and spatial average of the pressure, and establish a uniform-in-$m$ strict expansion property of the pressure supports. As a corollary, we derive upper bounds for the Hausdorff dimensions of the free boundaries and show that the limiting free boundary has finite $(d-1)$-dimensional Hausdorff measure. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2403_05804 |
| institution | arXiv |
| publishDate | 2024 |
| record_format | arxiv |
| spellingShingle | Convergence of Free Boundaries in the Incompressible Limit of Tumor Growth Models Tong, Jiajun Zhang, Yuming Paul Analysis of PDEs 35R35, 35K65, 49Q15, 76D27, 35B40, 35Q92 We investigate the general Porous Medium Equations with drift and source terms that model tumor growth. Incompressible limit of such models has been well-studied in the literature, where convergence of the density and pressure variables are established, while it remains unclear whether the free boundaries of the solutions exhibit convergence as well. In this paper, we provide an affirmative result by showing that the free boundaries converge in the Hausdorff distance in the incompressible limit. To achieve this, we quantify the relation between the free boundary motion and spatial average of the pressure, and establish a uniform-in-$m$ strict expansion property of the pressure supports. As a corollary, we derive upper bounds for the Hausdorff dimensions of the free boundaries and show that the limiting free boundary has finite $(d-1)$-dimensional Hausdorff measure. |
| title | Convergence of Free Boundaries in the Incompressible Limit of Tumor Growth Models |
| topic | Analysis of PDEs 35R35, 35K65, 49Q15, 76D27, 35B40, 35Q92 |
| url | https://arxiv.org/abs/2403.05804 |