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Main Authors: Somathilaka, Samitha, Ratwatte, Adrian, Balasubramaniam, Sasitharan, Vuran, Mehmet Can, Srisa-an, Witawas, Liò, Pietro
Format: Preprint
Published: 2024
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Online Access:https://arxiv.org/abs/2403.08549
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author Somathilaka, Samitha
Ratwatte, Adrian
Balasubramaniam, Sasitharan
Vuran, Mehmet Can
Srisa-an, Witawas
Liò, Pietro
author_facet Somathilaka, Samitha
Ratwatte, Adrian
Balasubramaniam, Sasitharan
Vuran, Mehmet Can
Srisa-an, Witawas
Liò, Pietro
contents In our earlier work, we introduced the concept of Gene Regulatory Neural Network (GRNN), which utilizes natural neural network-like structures inherent in biological cells to perform computing tasks using chemical inputs. We define this form of chemical-based neural network as Wet TinyML. The GRNN structures are based on the gene regulatory network and have weights associated with each link based on the estimated interactions between the genes. The GRNNs can be used for conventional computing by employing an application-based search process similar to the Network Architecture Search. This study advances this concept by incorporating cell plasticity, to further exploit natural cell's adaptability, in order to diversify the GRNN search that can match larger spectrum as well as dynamic computing tasks. As an example application, we show that through the directed cell plasticity, we can extract the mathematical regression evolution enabling it to match to dynamic system applications. We also conduct energy analysis by comparing the chemical energy of the GRNN to its silicon counterpart, where this analysis includes both artificial neural network algorithms executed on von Neumann architecture as well as neuromorphic processors. The concept of Wet TinyML can pave the way for the new emergence of chemical-based, energy-efficient and miniature Biological AI.
format Preprint
id arxiv_https___arxiv_org_abs_2403_08549
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Wet TinyML: Chemical Neural Network Using Gene Regulation and Cell Plasticity
Somathilaka, Samitha
Ratwatte, Adrian
Balasubramaniam, Sasitharan
Vuran, Mehmet Can
Srisa-an, Witawas
Liò, Pietro
Neural and Evolutionary Computing
Hardware Architecture
In our earlier work, we introduced the concept of Gene Regulatory Neural Network (GRNN), which utilizes natural neural network-like structures inherent in biological cells to perform computing tasks using chemical inputs. We define this form of chemical-based neural network as Wet TinyML. The GRNN structures are based on the gene regulatory network and have weights associated with each link based on the estimated interactions between the genes. The GRNNs can be used for conventional computing by employing an application-based search process similar to the Network Architecture Search. This study advances this concept by incorporating cell plasticity, to further exploit natural cell's adaptability, in order to diversify the GRNN search that can match larger spectrum as well as dynamic computing tasks. As an example application, we show that through the directed cell plasticity, we can extract the mathematical regression evolution enabling it to match to dynamic system applications. We also conduct energy analysis by comparing the chemical energy of the GRNN to its silicon counterpart, where this analysis includes both artificial neural network algorithms executed on von Neumann architecture as well as neuromorphic processors. The concept of Wet TinyML can pave the way for the new emergence of chemical-based, energy-efficient and miniature Biological AI.
title Wet TinyML: Chemical Neural Network Using Gene Regulation and Cell Plasticity
topic Neural and Evolutionary Computing
Hardware Architecture
url https://arxiv.org/abs/2403.08549