Depth-induced Saliency Comparison Network for Diagnosis of Alzheimer's Disease via Jointly Analysis of Visual Stimuli and Eye Movements

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Main Authors: Liu, Yu, Zhang, Wenlin, Wang, Shaochu, Zuo, Fangyu, Jing, Peiguang, Ji, Yong
Format: Preprint
Published: 2024
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author Liu, Yu
Zhang, Wenlin
Wang, Shaochu
Zuo, Fangyu
Jing, Peiguang
Ji, Yong
author_facet Liu, Yu
Zhang, Wenlin
Wang, Shaochu
Zuo, Fangyu
Jing, Peiguang
Ji, Yong
contents Early diagnosis of Alzheimer's Disease (AD) is very important for following medical treatments, and eye movements under special visual stimuli may serve as a potential non-invasive biomarker for detecting cognitive abnormalities of AD patients. In this paper, we propose an Depth-induced saliency comparison network (DISCN) for eye movement analysis, which may be used for diagnosis the Alzheimers disease. In DISCN, a salient attention module fuses normal eye movements with RGB and depth maps of visual stimuli using hierarchical salient attention (SAA) to evaluate comprehensive saliency maps, which contain information from both visual stimuli and normal eye movement behaviors. In addition, we introduce serial attention module (SEA) to emphasis the most abnormal eye movement behaviors to reduce personal bias for a more robust result. According to our experiments, the DISCN achieves consistent validity in classifying the eye movements between the AD patients and normal controls.
format Preprint
id arxiv_https___arxiv_org_abs_2403_10124
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Depth-induced Saliency Comparison Network for Diagnosis of Alzheimer's Disease via Jointly Analysis of Visual Stimuli and Eye Movements
Liu, Yu
Zhang, Wenlin
Wang, Shaochu
Zuo, Fangyu
Jing, Peiguang
Ji, Yong
Computer Vision and Pattern Recognition
Early diagnosis of Alzheimer's Disease (AD) is very important for following medical treatments, and eye movements under special visual stimuli may serve as a potential non-invasive biomarker for detecting cognitive abnormalities of AD patients. In this paper, we propose an Depth-induced saliency comparison network (DISCN) for eye movement analysis, which may be used for diagnosis the Alzheimers disease. In DISCN, a salient attention module fuses normal eye movements with RGB and depth maps of visual stimuli using hierarchical salient attention (SAA) to evaluate comprehensive saliency maps, which contain information from both visual stimuli and normal eye movement behaviors. In addition, we introduce serial attention module (SEA) to emphasis the most abnormal eye movement behaviors to reduce personal bias for a more robust result. According to our experiments, the DISCN achieves consistent validity in classifying the eye movements between the AD patients and normal controls.
title Depth-induced Saliency Comparison Network for Diagnosis of Alzheimer's Disease via Jointly Analysis of Visual Stimuli and Eye Movements
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2403.10124