Stitching, Fine-tuning, Re-training: A SAM-enabled Framework for Semi-supervised 3D Medical Image Segmentation

Fuente: arXiv
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Autores principales: Li, Shumeng, Qi, Lei, Yu, Qian, Huo, Jing, Shi, Yinghuan, Gao, Yang
Formato: Preprint
Publicado: 2024
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author Li, Shumeng
Qi, Lei
Yu, Qian
Huo, Jing
Shi, Yinghuan
Gao, Yang
author_facet Li, Shumeng
Qi, Lei
Yu, Qian
Huo, Jing
Shi, Yinghuan
Gao, Yang
contents Segment Anything Model (SAM) fine-tuning has shown remarkable performance in medical image segmentation in a fully supervised manner, but requires precise annotations. To reduce the annotation cost and maintain satisfactory performance, in this work, we leverage the capabilities of SAM for establishing semi-supervised medical image segmentation models. Rethinking the requirements of effectiveness, efficiency, and compatibility, we propose a three-stage framework, i.e., Stitching, Fine-tuning, and Re-training (SFR). The current fine-tuning approaches mostly involve 2D slice-wise fine-tuning that disregards the contextual information between adjacent slices. Our stitching strategy mitigates the mismatch between natural and 3D medical images. The stitched images are then used for fine-tuning SAM, providing robust initialization of pseudo-labels. Afterwards, we train a 3D semi-supervised segmentation model while maintaining the same parameter size as the conventional segmenter such as V-Net. Our SFR framework is plug-and-play, and easily compatible with various popular semi-supervised methods. We also develop an extended framework SFR$^+$ with selective fine-tuning and re-training through confidence estimation. Extensive experiments validate that our SFR and SFR$^+$ achieve significant improvements in both moderate annotation and scarce annotation across five datasets. In particular, SFR framework improves the Dice score of Mean Teacher from 29.68% to 74.40% with only one labeled data of LA dataset.
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id arxiv_https___arxiv_org_abs_2403_11229
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publishDate 2024
record_format arxiv
spellingShingle Stitching, Fine-tuning, Re-training: A SAM-enabled Framework for Semi-supervised 3D Medical Image Segmentation
Li, Shumeng
Qi, Lei
Yu, Qian
Huo, Jing
Shi, Yinghuan
Gao, Yang
Computer Vision and Pattern Recognition
Segment Anything Model (SAM) fine-tuning has shown remarkable performance in medical image segmentation in a fully supervised manner, but requires precise annotations. To reduce the annotation cost and maintain satisfactory performance, in this work, we leverage the capabilities of SAM for establishing semi-supervised medical image segmentation models. Rethinking the requirements of effectiveness, efficiency, and compatibility, we propose a three-stage framework, i.e., Stitching, Fine-tuning, and Re-training (SFR). The current fine-tuning approaches mostly involve 2D slice-wise fine-tuning that disregards the contextual information between adjacent slices. Our stitching strategy mitigates the mismatch between natural and 3D medical images. The stitched images are then used for fine-tuning SAM, providing robust initialization of pseudo-labels. Afterwards, we train a 3D semi-supervised segmentation model while maintaining the same parameter size as the conventional segmenter such as V-Net. Our SFR framework is plug-and-play, and easily compatible with various popular semi-supervised methods. We also develop an extended framework SFR$^+$ with selective fine-tuning and re-training through confidence estimation. Extensive experiments validate that our SFR and SFR$^+$ achieve significant improvements in both moderate annotation and scarce annotation across five datasets. In particular, SFR framework improves the Dice score of Mean Teacher from 29.68% to 74.40% with only one labeled data of LA dataset.
title Stitching, Fine-tuning, Re-training: A SAM-enabled Framework for Semi-supervised 3D Medical Image Segmentation
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2403.11229