Deep Few-view High-resolution Photon-counting CT at Halved Dose for Extremity Imaging

Fuente: arXiv
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Main Authors: Li, Mengzhou, Niu, Chuang, Wang, Ge, Amma, Maya R, Chapagain, Krishna M, Gabrielson, Stefan, Li, Andrew, Jonker, Kevin, de Ruiter, Niels, Clark, Jennifer A, Butler, Phil, Butler, Anthony, Yu, Hengyong
Format: Preprint
Published: 2024
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author Li, Mengzhou
Niu, Chuang
Wang, Ge
Amma, Maya R
Chapagain, Krishna M
Gabrielson, Stefan
Li, Andrew
Jonker, Kevin
de Ruiter, Niels
Clark, Jennifer A
Butler, Phil
Butler, Anthony
Yu, Hengyong
author_facet Li, Mengzhou
Niu, Chuang
Wang, Ge
Amma, Maya R
Chapagain, Krishna M
Gabrielson, Stefan
Li, Andrew
Jonker, Kevin
de Ruiter, Niels
Clark, Jennifer A
Butler, Phil
Butler, Anthony
Yu, Hengyong
contents X-ray photon-counting computed tomography (PCCT) for extremity allows multi-energy high-resolution (HR) imaging but its radiation dose can be further improved. Despite the great potential of deep learning techniques, their application in HR volumetric PCCT reconstruction has been challenged by the large memory burden, training data scarcity, and domain gap issues. In this paper, we propose a deep learning-based approach for PCCT image reconstruction at halved dose and doubled speed validated in a New Zealand clinical trial. Specifically, we design a patch-based volumetric refinement network to alleviate the GPU memory limitation, train network with synthetic data, and use model-based iterative refinement to bridge the gap between synthetic and clinical data. Our results in a reader study of 8 patients from the clinical trial demonstrate a great potential to cut the radiation dose to half that of the clinical PCCT standard without compromising image quality and diagnostic value.
format Preprint
id arxiv_https___arxiv_org_abs_2403_12331
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Deep Few-view High-resolution Photon-counting CT at Halved Dose for Extremity Imaging
Li, Mengzhou
Niu, Chuang
Wang, Ge
Amma, Maya R
Chapagain, Krishna M
Gabrielson, Stefan
Li, Andrew
Jonker, Kevin
de Ruiter, Niels
Clark, Jennifer A
Butler, Phil
Butler, Anthony
Yu, Hengyong
Medical Physics
Computer Vision and Pattern Recognition
X-ray photon-counting computed tomography (PCCT) for extremity allows multi-energy high-resolution (HR) imaging but its radiation dose can be further improved. Despite the great potential of deep learning techniques, their application in HR volumetric PCCT reconstruction has been challenged by the large memory burden, training data scarcity, and domain gap issues. In this paper, we propose a deep learning-based approach for PCCT image reconstruction at halved dose and doubled speed validated in a New Zealand clinical trial. Specifically, we design a patch-based volumetric refinement network to alleviate the GPU memory limitation, train network with synthetic data, and use model-based iterative refinement to bridge the gap between synthetic and clinical data. Our results in a reader study of 8 patients from the clinical trial demonstrate a great potential to cut the radiation dose to half that of the clinical PCCT standard without compromising image quality and diagnostic value.
title Deep Few-view High-resolution Photon-counting CT at Halved Dose for Extremity Imaging
topic Medical Physics
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2403.12331