Cell Tracking in C. elegans with Cell Position Heatmap-Based Alignment and Pairwise Detection

Fuente: arXiv
Enregistré dans:
Détails bibliographiques
Auteurs principaux: Shiku, Kaito, Shirai, Hiromitsu, Ishihara, Takeshi, Bise, Ryoma
Format: Preprint
Publié: 2024
Sujets:
Accès en ligne:
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
_version_ 1866916167923269632
author Shiku, Kaito
Shirai, Hiromitsu
Ishihara, Takeshi
Bise, Ryoma
author_facet Shiku, Kaito
Shirai, Hiromitsu
Ishihara, Takeshi
Bise, Ryoma
contents 3D cell tracking in a living organism has a crucial role in live cell image analysis. Cell tracking in C. elegans has two difficulties. First, cell migration in a consecutive frame is large since they move their head during scanning. Second, cell detection is often inconsistent in consecutive frames due to touching cells and low-contrast images, and these inconsistent detections affect the tracking performance worse. In this paper, we propose a cell tracking method to address these issues, which has two main contributions. First, we introduce cell position heatmap-based non-rigid alignment with test-time fine-tuning, which can warp the detected points to near the positions at the next frame. Second, we propose a pairwise detection method, which uses the information of detection results at the previous frame for detecting cells at the current frame. The experimental results demonstrate the effectiveness of each module, and the proposed method achieved the best performance in comparison.
format Preprint
id arxiv_https___arxiv_org_abs_2403_13412
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Cell Tracking in C. elegans with Cell Position Heatmap-Based Alignment and Pairwise Detection
Shiku, Kaito
Shirai, Hiromitsu
Ishihara, Takeshi
Bise, Ryoma
Computer Vision and Pattern Recognition
3D cell tracking in a living organism has a crucial role in live cell image analysis. Cell tracking in C. elegans has two difficulties. First, cell migration in a consecutive frame is large since they move their head during scanning. Second, cell detection is often inconsistent in consecutive frames due to touching cells and low-contrast images, and these inconsistent detections affect the tracking performance worse. In this paper, we propose a cell tracking method to address these issues, which has two main contributions. First, we introduce cell position heatmap-based non-rigid alignment with test-time fine-tuning, which can warp the detected points to near the positions at the next frame. Second, we propose a pairwise detection method, which uses the information of detection results at the previous frame for detecting cells at the current frame. The experimental results demonstrate the effectiveness of each module, and the proposed method achieved the best performance in comparison.
title Cell Tracking in C. elegans with Cell Position Heatmap-Based Alignment and Pairwise Detection
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2403.13412