Diversified and Personalized Multi-rater Medical Image Segmentation

Fuente: arXiv
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Main Authors: Wu, Yicheng, Luo, Xiangde, Xu, Zhe, Guo, Xiaoqing, Ju, Lie, Ge, Zongyuan, Liao, Wenjun, Cai, Jianfei
Format: Preprint
Published: 2024
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author Wu, Yicheng
Luo, Xiangde
Xu, Zhe
Guo, Xiaoqing
Ju, Lie
Ge, Zongyuan
Liao, Wenjun
Cai, Jianfei
author_facet Wu, Yicheng
Luo, Xiangde
Xu, Zhe
Guo, Xiaoqing
Ju, Lie
Ge, Zongyuan
Liao, Wenjun
Cai, Jianfei
contents Annotation ambiguity due to inherent data uncertainties such as blurred boundaries in medical scans and different observer expertise and preferences has become a major obstacle for training deep-learning based medical image segmentation models. To address it, the common practice is to gather multiple annotations from different experts, leading to the setting of multi-rater medical image segmentation. Existing works aim to either merge different annotations into the "groundtruth" that is often unattainable in numerous medical contexts, or generate diverse results, or produce personalized results corresponding to individual expert raters. Here, we bring up a more ambitious goal for multi-rater medical image segmentation, i.e., obtaining both diversified and personalized results. Specifically, we propose a two-stage framework named D-Persona (first Diversification and then Personalization). In Stage I, we exploit multiple given annotations to train a Probabilistic U-Net model, with a bound-constrained loss to improve the prediction diversity. In this way, a common latent space is constructed in Stage I, where different latent codes denote diversified expert opinions. Then, in Stage II, we design multiple attention-based projection heads to adaptively query the corresponding expert prompts from the shared latent space, and then perform the personalized medical image segmentation. We evaluated the proposed model on our in-house Nasopharyngeal Carcinoma dataset and the public lung nodule dataset (i.e., LIDC-IDRI). Extensive experiments demonstrated our D-Persona can provide diversified and personalized results at the same time, achieving new SOTA performance for multi-rater medical image segmentation. Our code will be released at https://github.com/ycwu1997/D-Persona.
format Preprint
id arxiv_https___arxiv_org_abs_2403_13417
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Diversified and Personalized Multi-rater Medical Image Segmentation
Wu, Yicheng
Luo, Xiangde
Xu, Zhe
Guo, Xiaoqing
Ju, Lie
Ge, Zongyuan
Liao, Wenjun
Cai, Jianfei
Computer Vision and Pattern Recognition
Annotation ambiguity due to inherent data uncertainties such as blurred boundaries in medical scans and different observer expertise and preferences has become a major obstacle for training deep-learning based medical image segmentation models. To address it, the common practice is to gather multiple annotations from different experts, leading to the setting of multi-rater medical image segmentation. Existing works aim to either merge different annotations into the "groundtruth" that is often unattainable in numerous medical contexts, or generate diverse results, or produce personalized results corresponding to individual expert raters. Here, we bring up a more ambitious goal for multi-rater medical image segmentation, i.e., obtaining both diversified and personalized results. Specifically, we propose a two-stage framework named D-Persona (first Diversification and then Personalization). In Stage I, we exploit multiple given annotations to train a Probabilistic U-Net model, with a bound-constrained loss to improve the prediction diversity. In this way, a common latent space is constructed in Stage I, where different latent codes denote diversified expert opinions. Then, in Stage II, we design multiple attention-based projection heads to adaptively query the corresponding expert prompts from the shared latent space, and then perform the personalized medical image segmentation. We evaluated the proposed model on our in-house Nasopharyngeal Carcinoma dataset and the public lung nodule dataset (i.e., LIDC-IDRI). Extensive experiments demonstrated our D-Persona can provide diversified and personalized results at the same time, achieving new SOTA performance for multi-rater medical image segmentation. Our code will be released at https://github.com/ycwu1997/D-Persona.
title Diversified and Personalized Multi-rater Medical Image Segmentation
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2403.13417