Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Gheshlaghi, Saba Heidari, Aryal, Milan, Yahyasoltani, Nasim, Ganji, Masoud
Format: Preprint
Veröffentlicht: 2024
Schlagworte:
Online-Zugang:https://arxiv.org/abs/2403.14489
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
_version_ 1866911807415779328
author Gheshlaghi, Saba Heidari
Aryal, Milan
Yahyasoltani, Nasim
Ganji, Masoud
author_facet Gheshlaghi, Saba Heidari
Aryal, Milan
Yahyasoltani, Nasim
Ganji, Masoud
contents Enhancing the robustness of deep learning models against adversarial attacks is crucial, especially in critical domains like healthcare where significant financial interests heighten the risk of such attacks. Whole slide images (WSIs) are high-resolution, digitized versions of tissue samples mounted on glass slides, scanned using sophisticated imaging equipment. The digital analysis of WSIs presents unique challenges due to their gigapixel size and multi-resolution storage format. In this work, we aim at improving the robustness of cancer Gleason grading classification systems against adversarial attacks, addressing challenges at both the image and graph levels. As regards the proposed algorithm, we develop a novel and innovative graph-based model which utilizes GNN to extract features from the graph representation of WSIs. A denoising module, along with a pooling layer is incorporated to manage the impact of adversarial attacks on the WSIs. The process concludes with a transformer module that classifies various grades of prostate cancer based on the processed data. To assess the effectiveness of the proposed method, we conducted a comparative analysis using two scenarios. Initially, we trained and tested the model without the denoiser using WSIs that had not been exposed to any attack. We then introduced a range of attacks at either the image or graph level and processed them through the proposed network. The performance of the model was evaluated in terms of accuracy and kappa scores. The results from this comparison showed a significant improvement in cancer diagnosis accuracy, highlighting the robustness and efficiency of the proposed method in handling adversarial challenges in the context of medical imaging.
format Preprint
id arxiv_https___arxiv_org_abs_2403_14489
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Adversary-Robust Graph-Based Learning of WSIs
Gheshlaghi, Saba Heidari
Aryal, Milan
Yahyasoltani, Nasim
Ganji, Masoud
Computer Vision and Pattern Recognition
Enhancing the robustness of deep learning models against adversarial attacks is crucial, especially in critical domains like healthcare where significant financial interests heighten the risk of such attacks. Whole slide images (WSIs) are high-resolution, digitized versions of tissue samples mounted on glass slides, scanned using sophisticated imaging equipment. The digital analysis of WSIs presents unique challenges due to their gigapixel size and multi-resolution storage format. In this work, we aim at improving the robustness of cancer Gleason grading classification systems against adversarial attacks, addressing challenges at both the image and graph levels. As regards the proposed algorithm, we develop a novel and innovative graph-based model which utilizes GNN to extract features from the graph representation of WSIs. A denoising module, along with a pooling layer is incorporated to manage the impact of adversarial attacks on the WSIs. The process concludes with a transformer module that classifies various grades of prostate cancer based on the processed data. To assess the effectiveness of the proposed method, we conducted a comparative analysis using two scenarios. Initially, we trained and tested the model without the denoiser using WSIs that had not been exposed to any attack. We then introduced a range of attacks at either the image or graph level and processed them through the proposed network. The performance of the model was evaluated in terms of accuracy and kappa scores. The results from this comparison showed a significant improvement in cancer diagnosis accuracy, highlighting the robustness and efficiency of the proposed method in handling adversarial challenges in the context of medical imaging.
title Adversary-Robust Graph-Based Learning of WSIs
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2403.14489