RAmBLA: A Framework for Evaluating the Reliability of LLMs as Assistants in the Biomedical Domain

Fuente: arXiv
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Autores principales: Bolton, William James, Poyiadzi, Rafael, Morrell, Edward R., Bueno, Gabriela van Bergen Gonzalez, Goetz, Lea
Formato: Preprint
Publicado: 2024
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author Bolton, William James
Poyiadzi, Rafael
Morrell, Edward R.
Bueno, Gabriela van Bergen Gonzalez
Goetz, Lea
author_facet Bolton, William James
Poyiadzi, Rafael
Morrell, Edward R.
Bueno, Gabriela van Bergen Gonzalez
Goetz, Lea
contents Large Language Models (LLMs) increasingly support applications in a wide range of domains, some with potential high societal impact such as biomedicine, yet their reliability in realistic use cases is under-researched. In this work we introduce the Reliability AssesMent for Biomedical LLM Assistants (RAmBLA) framework and evaluate whether four state-of-the-art foundation LLMs can serve as reliable assistants in the biomedical domain. We identify prompt robustness, high recall, and a lack of hallucinations as necessary criteria for this use case. We design shortform tasks and tasks requiring LLM freeform responses mimicking real-world user interactions. We evaluate LLM performance using semantic similarity with a ground truth response, through an evaluator LLM.
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institution arXiv
publishDate 2024
record_format arxiv
spellingShingle RAmBLA: A Framework for Evaluating the Reliability of LLMs as Assistants in the Biomedical Domain
Bolton, William James
Poyiadzi, Rafael
Morrell, Edward R.
Bueno, Gabriela van Bergen Gonzalez
Goetz, Lea
Machine Learning
Artificial Intelligence
Large Language Models (LLMs) increasingly support applications in a wide range of domains, some with potential high societal impact such as biomedicine, yet their reliability in realistic use cases is under-researched. In this work we introduce the Reliability AssesMent for Biomedical LLM Assistants (RAmBLA) framework and evaluate whether four state-of-the-art foundation LLMs can serve as reliable assistants in the biomedical domain. We identify prompt robustness, high recall, and a lack of hallucinations as necessary criteria for this use case. We design shortform tasks and tasks requiring LLM freeform responses mimicking real-world user interactions. We evaluate LLM performance using semantic similarity with a ground truth response, through an evaluator LLM.
title RAmBLA: A Framework for Evaluating the Reliability of LLMs as Assistants in the Biomedical Domain
topic Machine Learning
Artificial Intelligence
url https://arxiv.org/abs/2403.14578