An early warning indicator trained on stochastic disease-spreading models with different noises

Fuente: arXiv
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Autori principali: Chakraborty, Amit K., Gao, Shan, Miry, Reza, Ramazi, Pouria, Greiner, Russell, Lewis, Mark A., Wang, Hao
Natura: Preprint
Pubblicazione: 2024
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author Chakraborty, Amit K.
Gao, Shan
Miry, Reza
Ramazi, Pouria
Greiner, Russell
Lewis, Mark A.
Wang, Hao
author_facet Chakraborty, Amit K.
Gao, Shan
Miry, Reza
Ramazi, Pouria
Greiner, Russell
Lewis, Mark A.
Wang, Hao
contents The timely detection of disease outbreaks through reliable early warning signals (EWSs) is indispensable for effective public health mitigation strategies. Nevertheless, the intricate dynamics of real-world disease spread, often influenced by diverse sources of noise and limited data in the early stages of outbreaks, pose a significant challenge in developing reliable EWSs, as the performance of existing indicators varies with extrinsic and intrinsic noises. Here, we address the challenge of modeling disease when the measurements are corrupted by additive white noise, multiplicative environmental noise, and demographic noise into a standard epidemic mathematical model. To navigate the complexities introduced by these noise sources, we employ a deep learning algorithm that provides EWS in infectious disease outbreak by training on noise-induced disease-spreading models. The indicator's effectiveness is demonstrated through its application to real-world COVID-19 cases in Edmonton and simulated time series derived from diverse disease spread models affected by noise. Notably, the indicator captures an impending transition in a time series of disease outbreaks and outperforms existing indicators. This study contributes to advancing early warning capabilities by addressing the intricate dynamics inherent in real-world disease spread, presenting a promising avenue for enhancing public health preparedness and response efforts.
format Preprint
id arxiv_https___arxiv_org_abs_2403_16233
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle An early warning indicator trained on stochastic disease-spreading models with different noises
Chakraborty, Amit K.
Gao, Shan
Miry, Reza
Ramazi, Pouria
Greiner, Russell
Lewis, Mark A.
Wang, Hao
Machine Learning
Populations and Evolution
Applications
The timely detection of disease outbreaks through reliable early warning signals (EWSs) is indispensable for effective public health mitigation strategies. Nevertheless, the intricate dynamics of real-world disease spread, often influenced by diverse sources of noise and limited data in the early stages of outbreaks, pose a significant challenge in developing reliable EWSs, as the performance of existing indicators varies with extrinsic and intrinsic noises. Here, we address the challenge of modeling disease when the measurements are corrupted by additive white noise, multiplicative environmental noise, and demographic noise into a standard epidemic mathematical model. To navigate the complexities introduced by these noise sources, we employ a deep learning algorithm that provides EWS in infectious disease outbreak by training on noise-induced disease-spreading models. The indicator's effectiveness is demonstrated through its application to real-world COVID-19 cases in Edmonton and simulated time series derived from diverse disease spread models affected by noise. Notably, the indicator captures an impending transition in a time series of disease outbreaks and outperforms existing indicators. This study contributes to advancing early warning capabilities by addressing the intricate dynamics inherent in real-world disease spread, presenting a promising avenue for enhancing public health preparedness and response efforts.
title An early warning indicator trained on stochastic disease-spreading models with different noises
topic Machine Learning
Populations and Evolution
Applications
url https://arxiv.org/abs/2403.16233