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| Main Authors: | , , , , , , , |
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| Format: | Preprint |
| Published: |
2024
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| Subjects: | |
| Online Access: | https://arxiv.org/abs/2403.17362 |
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| _version_ | 1866911813481791488 |
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| author | van Bohemen, Samuel J Rogers, Jeffrey M Alavanja, Aleksandra Evans, Andrew Young, Noel Boughton, Philip C Valderrama, Joaquin Kyme, Andre Z |
| author_facet | van Bohemen, Samuel J Rogers, Jeffrey M Alavanja, Aleksandra Evans, Andrew Young, Noel Boughton, Philip C Valderrama, Joaquin Kyme, Andre Z |
| contents | This study assessed the safety, feasibility, and acceptability of a novel device to monitor ischaemic stroke patients. The device captured electroencephalography (EEG) and electrocardiography (ECG) data to compute an ECG-based metric termed the Electrocardiography Brain Perfusion index (EBPi), which may function as a proxy for cerebral blood flow (CBF). Seventeen ischaemic stroke patients wore the device for nine hours and reported feedback at 1, 3, 6 and 9 hours regarding user experience, comfort, and satisfaction (acceptability). Safety was assessed as the number of adverse events reported. Feasibility was assessed as the percentage of uninterrupted EEG/ECG data recorded (data capture efficiency). No adverse events were reported, only minor incidences of discomfort. Overall device comfort (92.5% +/- 10.3%) and data capture efficiency (95.8% +/- 6.8%) were very high with relatively low variance. The device did not restrict participants from receiving clinical care and rarely (n=6) restricted participants from undertaking routine tasks. This study provides a promising evidence base for the deployment of the device in a clinical setting. If clinically validated, EBPi may be able to detect CBF changes to monitor early neurological deterioration and treatment outcomes, thus filling an important gap in current monitoring options. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2403_17362 |
| institution | arXiv |
| publishDate | 2024 |
| record_format | arxiv |
| spellingShingle | Safety, feasibility, and acceptability of a novel device to monitor ischaemic stroke patients van Bohemen, Samuel J Rogers, Jeffrey M Alavanja, Aleksandra Evans, Andrew Young, Noel Boughton, Philip C Valderrama, Joaquin Kyme, Andre Z Medical Physics This study assessed the safety, feasibility, and acceptability of a novel device to monitor ischaemic stroke patients. The device captured electroencephalography (EEG) and electrocardiography (ECG) data to compute an ECG-based metric termed the Electrocardiography Brain Perfusion index (EBPi), which may function as a proxy for cerebral blood flow (CBF). Seventeen ischaemic stroke patients wore the device for nine hours and reported feedback at 1, 3, 6 and 9 hours regarding user experience, comfort, and satisfaction (acceptability). Safety was assessed as the number of adverse events reported. Feasibility was assessed as the percentage of uninterrupted EEG/ECG data recorded (data capture efficiency). No adverse events were reported, only minor incidences of discomfort. Overall device comfort (92.5% +/- 10.3%) and data capture efficiency (95.8% +/- 6.8%) were very high with relatively low variance. The device did not restrict participants from receiving clinical care and rarely (n=6) restricted participants from undertaking routine tasks. This study provides a promising evidence base for the deployment of the device in a clinical setting. If clinically validated, EBPi may be able to detect CBF changes to monitor early neurological deterioration and treatment outcomes, thus filling an important gap in current monitoring options. |
| title | Safety, feasibility, and acceptability of a novel device to monitor ischaemic stroke patients |
| topic | Medical Physics |
| url | https://arxiv.org/abs/2403.17362 |