Does Biomedical Training Lead to Better Medical Performance?

Fuente: arXiv
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Autores principales: Dada, Amin, Bauer, Marie, Contreras, Amanda Butler, Koraş, Osman Alperen, Seibold, Constantin Marc, Smith, Kaleb E, Kleesiek, Jens
Formato: Preprint
Publicado: 2024
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author Dada, Amin
Bauer, Marie
Contreras, Amanda Butler
Koraş, Osman Alperen
Seibold, Constantin Marc
Smith, Kaleb E
Kleesiek, Jens
author_facet Dada, Amin
Bauer, Marie
Contreras, Amanda Butler
Koraş, Osman Alperen
Seibold, Constantin Marc
Smith, Kaleb E
Kleesiek, Jens
contents Large Language Models (LLMs) are expected to significantly contribute to patient care, diagnostics, and administrative processes. Emerging biomedical LLMs aim to address healthcare-specific challenges, including privacy demands and computational constraints. Assessing the models' suitability for this sensitive application area is of the utmost importance. However, biomedical training has not been systematically evaluated on medical tasks. This study investigates the effect of biomedical training in the context of six practical medical tasks evaluating $25$ models. In contrast to previous evaluations, our results reveal a performance decline in nine out of twelve biomedical models after fine-tuning, particularly on tasks involving hallucinations, ICD10 coding, and instruction adherence. General-domain models like Meta-Llama-3.1-70B-Instruct outperformed their biomedical counterparts, indicating a trade-off between domain-specific fine-tuning and general medical task performance. We open-source all evaluation scripts and datasets at https://github.com/TIO-IKIM/CLUE to support further research in this critical area.
format Preprint
id arxiv_https___arxiv_org_abs_2404_04067
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Does Biomedical Training Lead to Better Medical Performance?
Dada, Amin
Bauer, Marie
Contreras, Amanda Butler
Koraş, Osman Alperen
Seibold, Constantin Marc
Smith, Kaleb E
Kleesiek, Jens
Computation and Language
Artificial Intelligence
Machine Learning
Large Language Models (LLMs) are expected to significantly contribute to patient care, diagnostics, and administrative processes. Emerging biomedical LLMs aim to address healthcare-specific challenges, including privacy demands and computational constraints. Assessing the models' suitability for this sensitive application area is of the utmost importance. However, biomedical training has not been systematically evaluated on medical tasks. This study investigates the effect of biomedical training in the context of six practical medical tasks evaluating $25$ models. In contrast to previous evaluations, our results reveal a performance decline in nine out of twelve biomedical models after fine-tuning, particularly on tasks involving hallucinations, ICD10 coding, and instruction adherence. General-domain models like Meta-Llama-3.1-70B-Instruct outperformed their biomedical counterparts, indicating a trade-off between domain-specific fine-tuning and general medical task performance. We open-source all evaluation scripts and datasets at https://github.com/TIO-IKIM/CLUE to support further research in this critical area.
title Does Biomedical Training Lead to Better Medical Performance?
topic Computation and Language
Artificial Intelligence
Machine Learning
url https://arxiv.org/abs/2404.04067