How Consistent are Clinicians? Evaluating the Predictability of Sepsis Disease Progression with Dynamics Models

Fuente: arXiv
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Autori principali: Park, Unnseo, Sivaraman, Venkatesh, Perer, Adam
Natura: Preprint
Pubblicazione: 2024
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author Park, Unnseo
Sivaraman, Venkatesh
Perer, Adam
author_facet Park, Unnseo
Sivaraman, Venkatesh
Perer, Adam
contents Reinforcement learning (RL) is a promising approach to generate treatment policies for sepsis patients in intensive care. While retrospective evaluation metrics show decreased mortality when these policies are followed, studies with clinicians suggest their recommendations are often spurious. We propose that these shortcomings may be due to lack of diversity in observed actions and outcomes in the training data, and we construct experiments to investigate the feasibility of predicting sepsis disease severity changes due to clinician actions. Preliminary results suggest incorporating action information does not significantly improve model performance, indicating that clinician actions may not be sufficiently variable to yield measurable effects on disease progression. We discuss the implications of these findings for optimizing sepsis treatment.
format Preprint
id arxiv_https___arxiv_org_abs_2404_07148
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle How Consistent are Clinicians? Evaluating the Predictability of Sepsis Disease Progression with Dynamics Models
Park, Unnseo
Sivaraman, Venkatesh
Perer, Adam
Machine Learning
Human-Computer Interaction
Reinforcement learning (RL) is a promising approach to generate treatment policies for sepsis patients in intensive care. While retrospective evaluation metrics show decreased mortality when these policies are followed, studies with clinicians suggest their recommendations are often spurious. We propose that these shortcomings may be due to lack of diversity in observed actions and outcomes in the training data, and we construct experiments to investigate the feasibility of predicting sepsis disease severity changes due to clinician actions. Preliminary results suggest incorporating action information does not significantly improve model performance, indicating that clinician actions may not be sufficiently variable to yield measurable effects on disease progression. We discuss the implications of these findings for optimizing sepsis treatment.
title How Consistent are Clinicians? Evaluating the Predictability of Sepsis Disease Progression with Dynamics Models
topic Machine Learning
Human-Computer Interaction
url https://arxiv.org/abs/2404.07148