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Bibliographic Details
Main Authors: Jiang, Qianqian, Li, Wenbo, Li, Zeng
Format: Preprint
Published: 2024
Subjects:
Online Access:https://arxiv.org/abs/2404.08355
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Table of Contents:
  • We investigate one/two-sample mean tests for high-dimensional compositional data when the number of variables is comparable with the sample size, as commonly encountered in microbiome research. Existing methods mainly focus on max-type test statistics which are suitable for detecting sparse signals. However, in this paper, we introduce a novel approach using sum-type test statistics which are capable of detecting weak but dense signals. By establishing the asymptotic independence between the max-type and sum-type test statistics, we further propose a combined max-sum type test to cover both cases. We derived the asymptotic null distributions and power functions for these test statistics. Simulation studies demonstrate the superiority of our max-sum type test statistics which exhibit robust performance regardless of data sparsity.