How to build the best medical image segmentation algorithm using foundation models: a comprehensive empirical study with Segment Anything Model

Fuente: arXiv
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Autori principali: Gu, Hanxue, Dong, Haoyu, Yang, Jichen, Mazurowski, Maciej A.
Natura: Preprint
Pubblicazione: 2024
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author Gu, Hanxue
Dong, Haoyu
Yang, Jichen
Mazurowski, Maciej A.
author_facet Gu, Hanxue
Dong, Haoyu
Yang, Jichen
Mazurowski, Maciej A.
contents Automated segmentation is a fundamental medical image analysis task, which enjoys significant advances due to the advent of deep learning. While foundation models have been useful in natural language processing and some vision tasks for some time, the foundation model developed with image segmentation in mind - Segment Anything Model (SAM) - has been developed only recently and has shown similar promise. However, there are still no systematic analyses or "best-practice" guidelines for optimal fine-tuning of SAM for medical image segmentation. This work summarizes existing fine-tuning strategies with various backbone architectures, model components, and fine-tuning algorithms across 18 combinations, and evaluates them on 17 datasets covering all common radiology modalities. Our study reveals that (1) fine-tuning SAM leads to slightly better performance than previous segmentation methods, (2) fine-tuning strategies that use parameter-efficient learning in both the encoder and decoder are superior to other strategies, (3) network architecture has a small impact on final performance, (4) further training SAM with self-supervised learning can improve final model performance. We also demonstrate the ineffectiveness of some methods popular in the literature and further expand our experiments into few-shot and prompt-based settings. Lastly, we released our code and MRI-specific fine-tuned weights, which consistently obtained superior performance over the original SAM, at https://github.com/mazurowski-lab/finetune-SAM.
format Preprint
id arxiv_https___arxiv_org_abs_2404_09957
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle How to build the best medical image segmentation algorithm using foundation models: a comprehensive empirical study with Segment Anything Model
Gu, Hanxue
Dong, Haoyu
Yang, Jichen
Mazurowski, Maciej A.
Computer Vision and Pattern Recognition
Machine Learning
Automated segmentation is a fundamental medical image analysis task, which enjoys significant advances due to the advent of deep learning. While foundation models have been useful in natural language processing and some vision tasks for some time, the foundation model developed with image segmentation in mind - Segment Anything Model (SAM) - has been developed only recently and has shown similar promise. However, there are still no systematic analyses or "best-practice" guidelines for optimal fine-tuning of SAM for medical image segmentation. This work summarizes existing fine-tuning strategies with various backbone architectures, model components, and fine-tuning algorithms across 18 combinations, and evaluates them on 17 datasets covering all common radiology modalities. Our study reveals that (1) fine-tuning SAM leads to slightly better performance than previous segmentation methods, (2) fine-tuning strategies that use parameter-efficient learning in both the encoder and decoder are superior to other strategies, (3) network architecture has a small impact on final performance, (4) further training SAM with self-supervised learning can improve final model performance. We also demonstrate the ineffectiveness of some methods popular in the literature and further expand our experiments into few-shot and prompt-based settings. Lastly, we released our code and MRI-specific fine-tuned weights, which consistently obtained superior performance over the original SAM, at https://github.com/mazurowski-lab/finetune-SAM.
title How to build the best medical image segmentation algorithm using foundation models: a comprehensive empirical study with Segment Anything Model
topic Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2404.09957