Photonic Neuromorphic Accelerators for Event-Based Imaging Flow Cytometry

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Hauptverfasser: Tsilikas, Ioannis, Tsirigotis, Aris, Sarantoglou, George, Deligiannidis, Stavros, Bogris, Adonis, Posch, Christoph, Branden, Gerd Van den, Mesaritakis, Charis
Format: Preprint
Veröffentlicht: 2024
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author Tsilikas, Ioannis
Tsirigotis, Aris
Sarantoglou, George
Deligiannidis, Stavros
Bogris, Adonis
Posch, Christoph
Branden, Gerd Van den
Mesaritakis, Charis
author_facet Tsilikas, Ioannis
Tsirigotis, Aris
Sarantoglou, George
Deligiannidis, Stavros
Bogris, Adonis
Posch, Christoph
Branden, Gerd Van den
Mesaritakis, Charis
contents In this work, we present experimental results of a high-speed label-free imaging cytometry system that seamlessly merges the high-capturing rate and data sparsity of an event-based CMOS camera with lightweight photonic neuromorphic processing. This combination offers high classification accuracy and a massive reduction in the number of trainable parameters of the digital machine-learning back-end. The photonic neuromorphic accelerator is based on a hardware-friendly passive optical spectrum slicing technique that is able to extract meaningful features from the generated spike-trains. The experimental scenario comprises the discrimination of artificial polymethyl methacrylate calibrated beads, having different diameters, flowing at a mean speed of 0.01m/sec. Classification accuracy, using only lightweight, digital machine-learning schemes has topped at 98.2%. On the other hand, by experimentally pre-processing the raw spike data through the proposed photonic neuromorphic spectrum slicer we achieved an accuracy of 98.6%. This performance was accompanied by a reduction in the number of trainable parameters at the classification back-end by a factor ranging from 8 to 22, depending on the configuration of the digital neural network.
format Preprint
id arxiv_https___arxiv_org_abs_2404_10564
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Photonic Neuromorphic Accelerators for Event-Based Imaging Flow Cytometry
Tsilikas, Ioannis
Tsirigotis, Aris
Sarantoglou, George
Deligiannidis, Stavros
Bogris, Adonis
Posch, Christoph
Branden, Gerd Van den
Mesaritakis, Charis
Optics
Image and Video Processing
In this work, we present experimental results of a high-speed label-free imaging cytometry system that seamlessly merges the high-capturing rate and data sparsity of an event-based CMOS camera with lightweight photonic neuromorphic processing. This combination offers high classification accuracy and a massive reduction in the number of trainable parameters of the digital machine-learning back-end. The photonic neuromorphic accelerator is based on a hardware-friendly passive optical spectrum slicing technique that is able to extract meaningful features from the generated spike-trains. The experimental scenario comprises the discrimination of artificial polymethyl methacrylate calibrated beads, having different diameters, flowing at a mean speed of 0.01m/sec. Classification accuracy, using only lightweight, digital machine-learning schemes has topped at 98.2%. On the other hand, by experimentally pre-processing the raw spike data through the proposed photonic neuromorphic spectrum slicer we achieved an accuracy of 98.6%. This performance was accompanied by a reduction in the number of trainable parameters at the classification back-end by a factor ranging from 8 to 22, depending on the configuration of the digital neural network.
title Photonic Neuromorphic Accelerators for Event-Based Imaging Flow Cytometry
topic Optics
Image and Video Processing
url https://arxiv.org/abs/2404.10564