Personalized Heart Disease Detection via ECG Digital Twin Generation
Fuente:
arXiv
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| Autori principali: | , , , , , , , |
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| Natura: | Preprint |
| Pubblicazione: |
2024
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| Soggetti: | |
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| _version_ | 1866914792889909248 |
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| author | Hu, Yaojun Chen, Jintai Hu, Lianting Li, Dantong Yan, Jiahuan Ying, Haochao Liang, Huiying Wu, Jian |
| author_facet | Hu, Yaojun Chen, Jintai Hu, Lianting Li, Dantong Yan, Jiahuan Ying, Haochao Liang, Huiying Wu, Jian |
| contents | Heart diseases rank among the leading causes of global mortality, demonstrating a crucial need for early diagnosis and intervention. Most traditional electrocardiogram (ECG) based automated diagnosis methods are trained at population level, neglecting the customization of personalized ECGs to enhance individual healthcare management. A potential solution to address this limitation is to employ digital twins to simulate symptoms of diseases in real patients. In this paper, we present an innovative prospective learning approach for personalized heart disease detection, which generates digital twins of healthy individuals' anomalous ECGs and enhances the model sensitivity to the personalized symptoms. In our approach, a vector quantized feature separator is proposed to locate and isolate the disease symptom and normal segments in ECG signals with ECG report guidance. Thus, the ECG digital twins can simulate specific heart diseases used to train a personalized heart disease detection model. Experiments demonstrate that our approach not only excels in generating high-fidelity ECG signals but also improves personalized heart disease detection. Moreover, our approach ensures robust privacy protection, safeguarding patient data in model development. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2404_11171 |
| institution | arXiv |
| publishDate | 2024 |
| record_format | arxiv |
| spellingShingle | Personalized Heart Disease Detection via ECG Digital Twin Generation Hu, Yaojun Chen, Jintai Hu, Lianting Li, Dantong Yan, Jiahuan Ying, Haochao Liang, Huiying Wu, Jian Machine Learning Artificial Intelligence Signal Processing Heart diseases rank among the leading causes of global mortality, demonstrating a crucial need for early diagnosis and intervention. Most traditional electrocardiogram (ECG) based automated diagnosis methods are trained at population level, neglecting the customization of personalized ECGs to enhance individual healthcare management. A potential solution to address this limitation is to employ digital twins to simulate symptoms of diseases in real patients. In this paper, we present an innovative prospective learning approach for personalized heart disease detection, which generates digital twins of healthy individuals' anomalous ECGs and enhances the model sensitivity to the personalized symptoms. In our approach, a vector quantized feature separator is proposed to locate and isolate the disease symptom and normal segments in ECG signals with ECG report guidance. Thus, the ECG digital twins can simulate specific heart diseases used to train a personalized heart disease detection model. Experiments demonstrate that our approach not only excels in generating high-fidelity ECG signals but also improves personalized heart disease detection. Moreover, our approach ensures robust privacy protection, safeguarding patient data in model development. |
| title | Personalized Heart Disease Detection via ECG Digital Twin Generation |
| topic | Machine Learning Artificial Intelligence Signal Processing |
| url | https://arxiv.org/abs/2404.11171 |