Analysis of blurring due to short T2 decay at different resolutions in 23Na MRI

Fuente: arXiv
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Autori principali: Dergachyova, Olga, Yu, Zidan, Hodono, Shota, Cloos, Martijn, Madelin, Guillaume
Natura: Preprint
Pubblicazione: 2024
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author Dergachyova, Olga
Yu, Zidan
Hodono, Shota
Cloos, Martijn
Madelin, Guillaume
author_facet Dergachyova, Olga
Yu, Zidan
Hodono, Shota
Cloos, Martijn
Madelin, Guillaume
contents The nuclear magnetic resonance signal from sodium (23Na) nuclei demonstrates a fast bi-exponential T2 decay in biological tissues (T2,short = 0.5-5 ms and T2,long = 10-30 ms). Hence, blurring observed in sodium images acquired with center-out sequences is generally assumed to be dominated by signal attenuation at higher k-space frequencies. Most of the studies in the field primarily focus on the impact of readout duration on blurring but neglect the impact of resolution. In this paper, we examine the blurring effect of short T2 on images at different resolutions. A series of simulations, as well as phantom and in vivo scans were performed at varying resolutions and readout durations in order to evaluate progressive changes in image quality. We demonstrate that, given a fixed readout duration, T2 decay produces distinct blurring effects at different resolutions. Therefore, in addition to voxel size-dependent partial volume effects, the choice of resolution adds additional T2-dependent blurring.
format Preprint
id arxiv_https___arxiv_org_abs_2404_11774
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Analysis of blurring due to short T2 decay at different resolutions in 23Na MRI
Dergachyova, Olga
Yu, Zidan
Hodono, Shota
Cloos, Martijn
Madelin, Guillaume
Medical Physics
Biological Physics
The nuclear magnetic resonance signal from sodium (23Na) nuclei demonstrates a fast bi-exponential T2 decay in biological tissues (T2,short = 0.5-5 ms and T2,long = 10-30 ms). Hence, blurring observed in sodium images acquired with center-out sequences is generally assumed to be dominated by signal attenuation at higher k-space frequencies. Most of the studies in the field primarily focus on the impact of readout duration on blurring but neglect the impact of resolution. In this paper, we examine the blurring effect of short T2 on images at different resolutions. A series of simulations, as well as phantom and in vivo scans were performed at varying resolutions and readout durations in order to evaluate progressive changes in image quality. We demonstrate that, given a fixed readout duration, T2 decay produces distinct blurring effects at different resolutions. Therefore, in addition to voxel size-dependent partial volume effects, the choice of resolution adds additional T2-dependent blurring.
title Analysis of blurring due to short T2 decay at different resolutions in 23Na MRI
topic Medical Physics
Biological Physics
url https://arxiv.org/abs/2404.11774