Automated tomographic assessment of structural defects of freeze-dried pharmaceuticals
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arXiv
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| Autores principales: | , , , , , , , , |
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| Formato: | Preprint |
| Publicado: |
2024
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| _version_ | 1866914759533658112 |
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| author | Müller, Patric Sack, Achim Dümler, Jens Heckel, Michael Wenzel, Tim Siegert, Teresa Schuldt-Lieb, Sonja Gieseler, Henning Pöschel, Thorsten |
| author_facet | Müller, Patric Sack, Achim Dümler, Jens Heckel, Michael Wenzel, Tim Siegert, Teresa Schuldt-Lieb, Sonja Gieseler, Henning Pöschel, Thorsten |
| contents | The topology and surface characteristics of lyophilisates significantly impact the stability and reconstitutability of freeze-dried pharmaceuticals. Consequently, visual quality control of the product is imperative. However, this procedure is not only time-consuming and labor-intensive but also expensive and prone to errors. In this paper, we present an approach for fully automated, non-destructive inspection of freeze-dried pharmaceuticals, leveraging robotics, computed tomography, and machine learning. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2404_11867 |
| institution | arXiv |
| publishDate | 2024 |
| record_format | arxiv |
| spellingShingle | Automated tomographic assessment of structural defects of freeze-dried pharmaceuticals Müller, Patric Sack, Achim Dümler, Jens Heckel, Michael Wenzel, Tim Siegert, Teresa Schuldt-Lieb, Sonja Gieseler, Henning Pöschel, Thorsten Soft Condensed Matter Applied Physics The topology and surface characteristics of lyophilisates significantly impact the stability and reconstitutability of freeze-dried pharmaceuticals. Consequently, visual quality control of the product is imperative. However, this procedure is not only time-consuming and labor-intensive but also expensive and prone to errors. In this paper, we present an approach for fully automated, non-destructive inspection of freeze-dried pharmaceuticals, leveraging robotics, computed tomography, and machine learning. |
| title | Automated tomographic assessment of structural defects of freeze-dried pharmaceuticals |
| topic | Soft Condensed Matter Applied Physics |
| url | https://arxiv.org/abs/2404.11867 |