Adaptive Catalyst Discovery Using Multicriteria Bayesian Optimization with Representation Learning

Fuente: arXiv
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Main Authors: Chen, Jie, Ou, Pengfei, Chang, Yuxin, Zhang, Hengrui, Li, Xiao-Yan, Sargent, Edward H., Chen, Wei
Format: Preprint
Published: 2024
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author Chen, Jie
Ou, Pengfei
Chang, Yuxin
Zhang, Hengrui
Li, Xiao-Yan
Sargent, Edward H.
Chen, Wei
author_facet Chen, Jie
Ou, Pengfei
Chang, Yuxin
Zhang, Hengrui
Li, Xiao-Yan
Sargent, Edward H.
Chen, Wei
contents High-performance catalysts are crucial for sustainable energy conversion and human health. However, the discovery of catalysts faces challenges due to the absence of efficient approaches to navigating vast and high-dimensional structure and composition spaces. In this study, we propose a high-throughput computational catalyst screening approach integrating density functional theory (DFT) and Bayesian Optimization (BO). Within the BO framework, we propose an uncertainty-aware atomistic machine learning model, UPNet, which enables automated representation learning directly from high-dimensional catalyst structures and achieves principled uncertainty quantification. Utilizing a constrained expected improvement acquisition function, our BO framework simultaneously considers multiple evaluation criteria. Using the proposed methods, we explore catalyst discovery for the CO2 reduction reaction. The results demonstrate that our approach achieves high prediction accuracy, facilitates interpretable feature extraction, and enables multicriteria design optimization, leading to significant reduction of computing power and time (10x reduction of required DFT calculations) in high-performance catalyst discovery.
format Preprint
id arxiv_https___arxiv_org_abs_2404_12445
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Adaptive Catalyst Discovery Using Multicriteria Bayesian Optimization with Representation Learning
Chen, Jie
Ou, Pengfei
Chang, Yuxin
Zhang, Hengrui
Li, Xiao-Yan
Sargent, Edward H.
Chen, Wei
Machine Learning
Computational Engineering, Finance, and Science
Chemical Physics
High-performance catalysts are crucial for sustainable energy conversion and human health. However, the discovery of catalysts faces challenges due to the absence of efficient approaches to navigating vast and high-dimensional structure and composition spaces. In this study, we propose a high-throughput computational catalyst screening approach integrating density functional theory (DFT) and Bayesian Optimization (BO). Within the BO framework, we propose an uncertainty-aware atomistic machine learning model, UPNet, which enables automated representation learning directly from high-dimensional catalyst structures and achieves principled uncertainty quantification. Utilizing a constrained expected improvement acquisition function, our BO framework simultaneously considers multiple evaluation criteria. Using the proposed methods, we explore catalyst discovery for the CO2 reduction reaction. The results demonstrate that our approach achieves high prediction accuracy, facilitates interpretable feature extraction, and enables multicriteria design optimization, leading to significant reduction of computing power and time (10x reduction of required DFT calculations) in high-performance catalyst discovery.
title Adaptive Catalyst Discovery Using Multicriteria Bayesian Optimization with Representation Learning
topic Machine Learning
Computational Engineering, Finance, and Science
Chemical Physics
url https://arxiv.org/abs/2404.12445