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Autori principali: Nasiri-Sarvi, Ali, Trinh, Vincent Quoc-Huy, Rivaz, Hassan, Hosseini, Mahdi S.
Natura: Preprint
Pubblicazione: 2024
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Accesso online:https://arxiv.org/abs/2404.13222
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author Nasiri-Sarvi, Ali
Trinh, Vincent Quoc-Huy
Rivaz, Hassan
Hosseini, Mahdi S.
author_facet Nasiri-Sarvi, Ali
Trinh, Vincent Quoc-Huy
Rivaz, Hassan
Hosseini, Mahdi S.
contents Representation learning from Gigapixel Whole Slide Images (WSI) poses a significant challenge in computational pathology due to the complicated nature of tissue structures and the scarcity of labeled data. Multi-instance learning methods have addressed this challenge, leveraging image patches to classify slides utilizing pretrained models using Self-Supervised Learning (SSL) approaches. The performance of both SSL and MIL methods relies on the architecture of the feature encoder. This paper proposes leveraging the Vision Mamba (Vim) architecture, inspired by state space models, within the DINO framework for representation learning in computational pathology. We evaluate the performance of Vim against Vision Transformers (ViT) on the Camelyon16 dataset for both patch-level and slide-level classification. Our findings highlight Vim's enhanced performance compared to ViT, particularly at smaller scales, where Vim achieves an 8.21 increase in ROC AUC for models of similar size. An explainability analysis further highlights Vim's capabilities, which reveals that Vim uniquely emulates the pathologist workflow-unlike ViT. This alignment with human expert analysis highlights Vim's potential in practical diagnostic settings and contributes significantly to developing effective representation-learning algorithms in computational pathology. We release the codes and pretrained weights at \url{https://github.com/AtlasAnalyticsLab/Vim4Path}.
format Preprint
id arxiv_https___arxiv_org_abs_2404_13222
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Vim4Path: Self-Supervised Vision Mamba for Histopathology Images
Nasiri-Sarvi, Ali
Trinh, Vincent Quoc-Huy
Rivaz, Hassan
Hosseini, Mahdi S.
Image and Video Processing
Computer Vision and Pattern Recognition
Representation learning from Gigapixel Whole Slide Images (WSI) poses a significant challenge in computational pathology due to the complicated nature of tissue structures and the scarcity of labeled data. Multi-instance learning methods have addressed this challenge, leveraging image patches to classify slides utilizing pretrained models using Self-Supervised Learning (SSL) approaches. The performance of both SSL and MIL methods relies on the architecture of the feature encoder. This paper proposes leveraging the Vision Mamba (Vim) architecture, inspired by state space models, within the DINO framework for representation learning in computational pathology. We evaluate the performance of Vim against Vision Transformers (ViT) on the Camelyon16 dataset for both patch-level and slide-level classification. Our findings highlight Vim's enhanced performance compared to ViT, particularly at smaller scales, where Vim achieves an 8.21 increase in ROC AUC for models of similar size. An explainability analysis further highlights Vim's capabilities, which reveals that Vim uniquely emulates the pathologist workflow-unlike ViT. This alignment with human expert analysis highlights Vim's potential in practical diagnostic settings and contributes significantly to developing effective representation-learning algorithms in computational pathology. We release the codes and pretrained weights at \url{https://github.com/AtlasAnalyticsLab/Vim4Path}.
title Vim4Path: Self-Supervised Vision Mamba for Histopathology Images
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2404.13222