DAWN: Domain-Adaptive Weakly Supervised Nuclei Segmentation via Cross-Task Interactions

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Main Authors: Zhang, Ye, Wang, Yifeng, Fang, Zijie, Bian, Hao, Cai, Linghan, Wang, Ziyue, Zhang, Yongbing
Format: Preprint
Published: 2024
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author Zhang, Ye
Wang, Yifeng
Fang, Zijie
Bian, Hao
Cai, Linghan
Wang, Ziyue
Zhang, Yongbing
author_facet Zhang, Ye
Wang, Yifeng
Fang, Zijie
Bian, Hao
Cai, Linghan
Wang, Ziyue
Zhang, Yongbing
contents Weakly supervised segmentation methods have gained significant attention due to their ability to reduce the reliance on costly pixel-level annotations during model training. However, the current weakly supervised nuclei segmentation approaches typically follow a two-stage pseudo-label generation and network training process. The performance of the nuclei segmentation heavily relies on the quality of the generated pseudo-labels, thereby limiting its effectiveness. This paper introduces a novel domain-adaptive weakly supervised nuclei segmentation framework using cross-task interaction strategies to overcome the challenge of pseudo-label generation. Specifically, we utilize weakly annotated data to train an auxiliary detection task, which assists the domain adaptation of the segmentation network. To enhance the efficiency of domain adaptation, we design a consistent feature constraint module integrating prior knowledge from the source domain. Furthermore, we develop pseudo-label optimization and interactive training methods to improve the domain transfer capability. To validate the effectiveness of our proposed method, we conduct extensive comparative and ablation experiments on six datasets. The results demonstrate the superiority of our approach over existing weakly supervised approaches. Remarkably, our method achieves comparable or even better performance than fully supervised methods. Our code will be released in https://github.com/zhangye-zoe/DAWN.
format Preprint
id arxiv_https___arxiv_org_abs_2404_14956
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle DAWN: Domain-Adaptive Weakly Supervised Nuclei Segmentation via Cross-Task Interactions
Zhang, Ye
Wang, Yifeng
Fang, Zijie
Bian, Hao
Cai, Linghan
Wang, Ziyue
Zhang, Yongbing
Image and Video Processing
Computer Vision and Pattern Recognition
Weakly supervised segmentation methods have gained significant attention due to their ability to reduce the reliance on costly pixel-level annotations during model training. However, the current weakly supervised nuclei segmentation approaches typically follow a two-stage pseudo-label generation and network training process. The performance of the nuclei segmentation heavily relies on the quality of the generated pseudo-labels, thereby limiting its effectiveness. This paper introduces a novel domain-adaptive weakly supervised nuclei segmentation framework using cross-task interaction strategies to overcome the challenge of pseudo-label generation. Specifically, we utilize weakly annotated data to train an auxiliary detection task, which assists the domain adaptation of the segmentation network. To enhance the efficiency of domain adaptation, we design a consistent feature constraint module integrating prior knowledge from the source domain. Furthermore, we develop pseudo-label optimization and interactive training methods to improve the domain transfer capability. To validate the effectiveness of our proposed method, we conduct extensive comparative and ablation experiments on six datasets. The results demonstrate the superiority of our approach over existing weakly supervised approaches. Remarkably, our method achieves comparable or even better performance than fully supervised methods. Our code will be released in https://github.com/zhangye-zoe/DAWN.
title DAWN: Domain-Adaptive Weakly Supervised Nuclei Segmentation via Cross-Task Interactions
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2404.14956