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Bibliographic Details
Main Authors: Zamora-Vinaroz, Ana María, de Vera, Pablo, Abril, Isabel, Garcia-Molina, Rafael
Format: Preprint
Published: 2024
Subjects:
Online Access:https://arxiv.org/abs/2404.16667
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Table of Contents:
  • We have determined the depth-dose curve, the penetration range, and the water equivalent ratio (WER), for proton beams of clinical energies in cortical bone, by means of a detailed and accurate simulation that combines molecular dynamics and Monte Carlo techniques. The fundamental input quantities (stopping power and energy loss straggling) for the simulation were obtained from a reliable electronic excitation spectrum of the condensed-phase target, which takes into account the organic and mineral phases that form it. Our simulations with these inputs, that are in excellent agreement with the scarce data available for a cortical bone target, deviate from simulations performed using other stopping quantities, such as those provided by the International Commission on Radiation Units and Measurements (ICRU) in its widely used Report 49. The results of this work emphasize the importance of an accurate determination of the stopping quantities of cortical bone in order to advance towards the millimetric precision for the proton penetration ranges and deposited dose needed in radiotherapy.