Strategy of a separation technique for different particles with the same size and zeta potential: Application of non-additive Asakura-Oosawa theory

Fuente: arXiv
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Auteurs principaux: Ogasawara, Ikuma, Amano, Ken-ichi
Format: Preprint
Publié: 2024
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author Ogasawara, Ikuma
Amano, Ken-ichi
author_facet Ogasawara, Ikuma
Amano, Ken-ichi
contents In this letter, we use knowledge gained from our recent study to present a technique for separation of nanoparticles such as exosomes, anticancer drugs, and vaccines. The technique involves adding non-adsorptive polymers to a system in which two types of nanoparticles with the same size and zeta potential are dispersed. The different types of nanoparticles can be separated based on differences in their hydrophobicities and softness of the polymer. Using the non-additive Asakura-Oosawa theory and assuming a realistic model system, we were able to separate the two types of the particles with the same size and zeta potential in the model system.
format Preprint
id arxiv_https___arxiv_org_abs_2404_17117
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Strategy of a separation technique for different particles with the same size and zeta potential: Application of non-additive Asakura-Oosawa theory
Ogasawara, Ikuma
Amano, Ken-ichi
Soft Condensed Matter
Mesoscale and Nanoscale Physics
Materials Science
In this letter, we use knowledge gained from our recent study to present a technique for separation of nanoparticles such as exosomes, anticancer drugs, and vaccines. The technique involves adding non-adsorptive polymers to a system in which two types of nanoparticles with the same size and zeta potential are dispersed. The different types of nanoparticles can be separated based on differences in their hydrophobicities and softness of the polymer. Using the non-additive Asakura-Oosawa theory and assuming a realistic model system, we were able to separate the two types of the particles with the same size and zeta potential in the model system.
title Strategy of a separation technique for different particles with the same size and zeta potential: Application of non-additive Asakura-Oosawa theory
topic Soft Condensed Matter
Mesoscale and Nanoscale Physics
Materials Science
url https://arxiv.org/abs/2404.17117