An Explainable Deep Reinforcement Learning Model for Warfarin Maintenance Dosing Using Policy Distillation and Action Forging
Fuente:
arXiv
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Format: | Preprint |
| Veröffentlicht: |
2024
|
| Schlagworte: | |
| Online-Zugang: | |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| _version_ | 1866917651455934464 |
|---|---|
| author | Zadeh, Sadjad Anzabi Street, W. Nick Thomas, Barrett W. |
| author_facet | Zadeh, Sadjad Anzabi Street, W. Nick Thomas, Barrett W. |
| contents | Deep Reinforcement Learning is an effective tool for drug dosing for chronic condition management. However, the final protocol is generally a black box without any justification for its prescribed doses. This paper addresses this issue by proposing an explainable dosing protocol for warfarin using a Proximal Policy Optimization method combined with Policy Distillation. We introduce Action Forging as an effective tool to achieve explainability. Our focus is on the maintenance dosing protocol. Results show that the final model is as easy to understand and deploy as the current dosing protocols and outperforms the baseline dosing algorithms. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2404_17187 |
| institution | arXiv |
| publishDate | 2024 |
| record_format | arxiv |
| spellingShingle | An Explainable Deep Reinforcement Learning Model for Warfarin Maintenance Dosing Using Policy Distillation and Action Forging Zadeh, Sadjad Anzabi Street, W. Nick Thomas, Barrett W. Machine Learning Deep Reinforcement Learning is an effective tool for drug dosing for chronic condition management. However, the final protocol is generally a black box without any justification for its prescribed doses. This paper addresses this issue by proposing an explainable dosing protocol for warfarin using a Proximal Policy Optimization method combined with Policy Distillation. We introduce Action Forging as an effective tool to achieve explainability. Our focus is on the maintenance dosing protocol. Results show that the final model is as easy to understand and deploy as the current dosing protocols and outperforms the baseline dosing algorithms. |
| title | An Explainable Deep Reinforcement Learning Model for Warfarin Maintenance Dosing Using Policy Distillation and Action Forging |
| topic | Machine Learning |
| url | https://arxiv.org/abs/2404.17187 |