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Main Authors: Ifargan, Tal, Hafner, Lukas, Kern, Maor, Alcalay, Ori, Kishony, Roy
Format: Preprint
Published: 2024
Subjects:
Online Access:https://arxiv.org/abs/2404.17605
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author Ifargan, Tal
Hafner, Lukas
Kern, Maor
Alcalay, Ori
Kishony, Roy
author_facet Ifargan, Tal
Hafner, Lukas
Kern, Maor
Alcalay, Ori
Kishony, Roy
contents As AI promises to accelerate scientific discovery, it remains unclear whether fully AI-driven research is possible and whether it can adhere to key scientific values, such as transparency, traceability and verifiability. Mimicking human scientific practices, we built data-to-paper, an automation platform that guides interacting LLM agents through a complete stepwise research process, while programmatically back-tracing information flow and allowing human oversight and interactions. In autopilot mode, provided with annotated data alone, data-to-paper raised hypotheses, designed research plans, wrote and debugged analysis codes, generated and interpreted results, and created complete and information-traceable research papers. Even though research novelty was relatively limited, the process demonstrated autonomous generation of de novo quantitative insights from data. For simple research goals, a fully-autonomous cycle can create manuscripts which recapitulate peer-reviewed publications without major errors in about 80-90%, yet as goal complexity increases, human co-piloting becomes critical for assuring accuracy. Beyond the process itself, created manuscripts too are inherently verifiable, as information-tracing allows to programmatically chain results, methods and data. Our work thereby demonstrates a potential for AI-driven acceleration of scientific discovery while enhancing, rather than jeopardizing, traceability, transparency and verifiability.
format Preprint
id arxiv_https___arxiv_org_abs_2404_17605
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Autonomous LLM-driven research from data to human-verifiable research papers
Ifargan, Tal
Hafner, Lukas
Kern, Maor
Alcalay, Ori
Kishony, Roy
Other Quantitative Biology
Artificial Intelligence
As AI promises to accelerate scientific discovery, it remains unclear whether fully AI-driven research is possible and whether it can adhere to key scientific values, such as transparency, traceability and verifiability. Mimicking human scientific practices, we built data-to-paper, an automation platform that guides interacting LLM agents through a complete stepwise research process, while programmatically back-tracing information flow and allowing human oversight and interactions. In autopilot mode, provided with annotated data alone, data-to-paper raised hypotheses, designed research plans, wrote and debugged analysis codes, generated and interpreted results, and created complete and information-traceable research papers. Even though research novelty was relatively limited, the process demonstrated autonomous generation of de novo quantitative insights from data. For simple research goals, a fully-autonomous cycle can create manuscripts which recapitulate peer-reviewed publications without major errors in about 80-90%, yet as goal complexity increases, human co-piloting becomes critical for assuring accuracy. Beyond the process itself, created manuscripts too are inherently verifiable, as information-tracing allows to programmatically chain results, methods and data. Our work thereby demonstrates a potential for AI-driven acceleration of scientific discovery while enhancing, rather than jeopardizing, traceability, transparency and verifiability.
title Autonomous LLM-driven research from data to human-verifiable research papers
topic Other Quantitative Biology
Artificial Intelligence
url https://arxiv.org/abs/2404.17605