SPLICE -- Streamlining Digital Pathology Image Processing

Fuente: arXiv
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Auteurs principaux: Alsaafin, Areej, Nejat, Peyman, Shafique, Abubakr, Khan, Jibran, Alfasly, Saghir, Alabtah, Ghazal, Tizhoosh, H. R.
Format: Preprint
Publié: 2024
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author Alsaafin, Areej
Nejat, Peyman
Shafique, Abubakr
Khan, Jibran
Alfasly, Saghir
Alabtah, Ghazal
Tizhoosh, H. R.
author_facet Alsaafin, Areej
Nejat, Peyman
Shafique, Abubakr
Khan, Jibran
Alfasly, Saghir
Alabtah, Ghazal
Tizhoosh, H. R.
contents Digital pathology and the integration of artificial intelligence (AI) models have revolutionized histopathology, opening new opportunities. With the increasing availability of Whole Slide Images (WSIs), there's a growing demand for efficient retrieval, processing, and analysis of relevant images from vast biomedical archives. However, processing WSIs presents challenges due to their large size and content complexity. Full computer digestion of WSIs is impractical, and processing all patches individually is prohibitively expensive. In this paper, we propose an unsupervised patching algorithm, Sequential Patching Lattice for Image Classification and Enquiry (SPLICE). This novel approach condenses a histopathology WSI into a compact set of representative patches, forming a "collage" of WSI while minimizing redundancy. SPLICE prioritizes patch quality and uniqueness by sequentially analyzing a WSI and selecting non-redundant representative features. We evaluated SPLICE for search and match applications, demonstrating improved accuracy, reduced computation time, and storage requirements compared to existing state-of-the-art methods. As an unsupervised method, SPLICE effectively reduces storage requirements for representing tissue images by 50%. This reduction enables numerous algorithms in computational pathology to operate much more efficiently, paving the way for accelerated adoption of digital pathology.
format Preprint
id arxiv_https___arxiv_org_abs_2404_17704
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle SPLICE -- Streamlining Digital Pathology Image Processing
Alsaafin, Areej
Nejat, Peyman
Shafique, Abubakr
Khan, Jibran
Alfasly, Saghir
Alabtah, Ghazal
Tizhoosh, H. R.
Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
Digital pathology and the integration of artificial intelligence (AI) models have revolutionized histopathology, opening new opportunities. With the increasing availability of Whole Slide Images (WSIs), there's a growing demand for efficient retrieval, processing, and analysis of relevant images from vast biomedical archives. However, processing WSIs presents challenges due to their large size and content complexity. Full computer digestion of WSIs is impractical, and processing all patches individually is prohibitively expensive. In this paper, we propose an unsupervised patching algorithm, Sequential Patching Lattice for Image Classification and Enquiry (SPLICE). This novel approach condenses a histopathology WSI into a compact set of representative patches, forming a "collage" of WSI while minimizing redundancy. SPLICE prioritizes patch quality and uniqueness by sequentially analyzing a WSI and selecting non-redundant representative features. We evaluated SPLICE for search and match applications, demonstrating improved accuracy, reduced computation time, and storage requirements compared to existing state-of-the-art methods. As an unsupervised method, SPLICE effectively reduces storage requirements for representing tissue images by 50%. This reduction enables numerous algorithms in computational pathology to operate much more efficiently, paving the way for accelerated adoption of digital pathology.
title SPLICE -- Streamlining Digital Pathology Image Processing
topic Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2404.17704