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Autori principali: Han, Kaiqiao, Yang, Yi, Huang, Zijie, Kan, Xuan, Yang, Yang, Guo, Ying, He, Lifang, Zhan, Liang, Sun, Yizhou, Wang, Wei, Yang, Carl
Natura: Preprint
Pubblicazione: 2024
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Accesso online:https://arxiv.org/abs/2405.00077
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author Han, Kaiqiao
Yang, Yi
Huang, Zijie
Kan, Xuan
Yang, Yang
Guo, Ying
He, Lifang
Zhan, Liang
Sun, Yizhou
Wang, Wei
Yang, Carl
author_facet Han, Kaiqiao
Yang, Yi
Huang, Zijie
Kan, Xuan
Yang, Yang
Guo, Ying
He, Lifang
Zhan, Liang
Sun, Yizhou
Wang, Wei
Yang, Carl
contents Brain network analysis is vital for understanding the neural interactions regarding brain structures and functions, and identifying potential biomarkers for clinical phenotypes. However, widely used brain signals such as Blood Oxygen Level Dependent (BOLD) time series generated from functional Magnetic Resonance Imaging (fMRI) often manifest three challenges: (1) missing values, (2) irregular samples, and (3) sampling misalignment, due to instrumental limitations, impacting downstream brain network analysis and clinical outcome predictions. In this work, we propose a novel model called BrainODE to achieve continuous modeling of dynamic brain signals using Ordinary Differential Equations (ODE). By learning latent initial values and neural ODE functions from irregular time series, BrainODE effectively reconstructs brain signals at any time point, mitigating the aforementioned three data challenges of brain signals altogether. Comprehensive experimental results on real-world neuroimaging datasets demonstrate the superior performance of BrainODE and its capability of addressing the three data challenges.
format Preprint
id arxiv_https___arxiv_org_abs_2405_00077
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle BrainODE: Dynamic Brain Signal Analysis via Graph-Aided Neural Ordinary Differential Equations
Han, Kaiqiao
Yang, Yi
Huang, Zijie
Kan, Xuan
Yang, Yang
Guo, Ying
He, Lifang
Zhan, Liang
Sun, Yizhou
Wang, Wei
Yang, Carl
Machine Learning
Signal Processing
Brain network analysis is vital for understanding the neural interactions regarding brain structures and functions, and identifying potential biomarkers for clinical phenotypes. However, widely used brain signals such as Blood Oxygen Level Dependent (BOLD) time series generated from functional Magnetic Resonance Imaging (fMRI) often manifest three challenges: (1) missing values, (2) irregular samples, and (3) sampling misalignment, due to instrumental limitations, impacting downstream brain network analysis and clinical outcome predictions. In this work, we propose a novel model called BrainODE to achieve continuous modeling of dynamic brain signals using Ordinary Differential Equations (ODE). By learning latent initial values and neural ODE functions from irregular time series, BrainODE effectively reconstructs brain signals at any time point, mitigating the aforementioned three data challenges of brain signals altogether. Comprehensive experimental results on real-world neuroimaging datasets demonstrate the superior performance of BrainODE and its capability of addressing the three data challenges.
title BrainODE: Dynamic Brain Signal Analysis via Graph-Aided Neural Ordinary Differential Equations
topic Machine Learning
Signal Processing
url https://arxiv.org/abs/2405.00077