Stability analysis of a three-dimensional system of Topp model with diabetes
Fuente:
arXiv
Salvato in:
| Autori principali: | , |
|---|---|
| Natura: | Preprint |
| Pubblicazione: |
2024
|
| Soggetti: | |
| Accesso online: | |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
|
| _version_ | 1866929332825358336 |
|---|---|
| author | Boxonov, Z. S. Rozikov, U. A. |
| author_facet | Boxonov, Z. S. Rozikov, U. A. |
| contents | Mathematical models of glucose, insulin, and pancreatic $β$-cell mass dynamics are essential for understanding the physiological basis of type 2 diabetes. This paper investigates the Topp model's discrete-time dynamics to represent these interactions. We perform a comprehensive analysis of the system's trajectory, examining both local and global behavior. First, we establish the invariance of the positive trajectory and analyze the existence of fixed points. Then, we conduct a complete stability analysis, determining the local and global asymptotic stability of these fixed points. Finally, numerical examples validate the effectiveness and applicability of our theoretical findings. Additionally, we provide biological interpretations of our results. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2405_00323 |
| institution | arXiv |
| publishDate | 2024 |
| record_format | arxiv |
| spellingShingle | Stability analysis of a three-dimensional system of Topp model with diabetes Boxonov, Z. S. Rozikov, U. A. Dynamical Systems 39A12, 39A30, 92C50 Mathematical models of glucose, insulin, and pancreatic $β$-cell mass dynamics are essential for understanding the physiological basis of type 2 diabetes. This paper investigates the Topp model's discrete-time dynamics to represent these interactions. We perform a comprehensive analysis of the system's trajectory, examining both local and global behavior. First, we establish the invariance of the positive trajectory and analyze the existence of fixed points. Then, we conduct a complete stability analysis, determining the local and global asymptotic stability of these fixed points. Finally, numerical examples validate the effectiveness and applicability of our theoretical findings. Additionally, we provide biological interpretations of our results. |
| title | Stability analysis of a three-dimensional system of Topp model with diabetes |
| topic | Dynamical Systems 39A12, 39A30, 92C50 |
| url | https://arxiv.org/abs/2405.00323 |