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Main Authors: Li, Lingyao, Zhou, Jiayan, Gao, Zhenxiang, Hua, Wenyue, Fan, Lizhou, Yu, Huizi, Hagen, Loni, Zhang, Yongfeng, Assimes, Themistocles L., Hemphill, Libby, Ma, Siyuan
Format: Preprint
Published: 2024
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Online Access:https://arxiv.org/abs/2405.03066
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author Li, Lingyao
Zhou, Jiayan
Gao, Zhenxiang
Hua, Wenyue
Fan, Lizhou
Yu, Huizi
Hagen, Loni
Zhang, Yongfeng
Assimes, Themistocles L.
Hemphill, Libby
Ma, Siyuan
author_facet Li, Lingyao
Zhou, Jiayan
Gao, Zhenxiang
Hua, Wenyue
Fan, Lizhou
Yu, Huizi
Hagen, Loni
Zhang, Yongfeng
Assimes, Themistocles L.
Hemphill, Libby
Ma, Siyuan
contents Electronic Health Records (EHRs) play an important role in the healthcare system. However, their complexity and vast volume pose significant challenges to data interpretation and analysis. Recent advancements in Artificial Intelligence (AI), particularly the development of Large Language Models (LLMs), open up new opportunities for researchers in this domain. Although prior studies have demonstrated their potential in language understanding and processing in the context of EHRs, a comprehensive scoping review is lacking. This study aims to bridge this research gap by conducting a scoping review based on 329 related papers collected from OpenAlex. We first performed a bibliometric analysis to examine paper trends, model applications, and collaboration networks. Next, we manually reviewed and categorized each paper into one of the seven identified topics: named entity recognition, information extraction, text similarity, text summarization, text classification, dialogue system, and diagnosis and prediction. For each topic, we discussed the unique capabilities of LLMs, such as their ability to understand context, capture semantic relations, and generate human-like text. Finally, we highlighted several implications for researchers from the perspectives of data resources, prompt engineering, fine-tuning, performance measures, and ethical concerns. In conclusion, this study provides valuable insights into the potential of LLMs to transform EHR research and discusses their applications and ethical considerations.
format Preprint
id arxiv_https___arxiv_org_abs_2405_03066
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle A scoping review of using Large Language Models (LLMs) to investigate Electronic Health Records (EHRs)
Li, Lingyao
Zhou, Jiayan
Gao, Zhenxiang
Hua, Wenyue
Fan, Lizhou
Yu, Huizi
Hagen, Loni
Zhang, Yongfeng
Assimes, Themistocles L.
Hemphill, Libby
Ma, Siyuan
Emerging Technologies
Electronic Health Records (EHRs) play an important role in the healthcare system. However, their complexity and vast volume pose significant challenges to data interpretation and analysis. Recent advancements in Artificial Intelligence (AI), particularly the development of Large Language Models (LLMs), open up new opportunities for researchers in this domain. Although prior studies have demonstrated their potential in language understanding and processing in the context of EHRs, a comprehensive scoping review is lacking. This study aims to bridge this research gap by conducting a scoping review based on 329 related papers collected from OpenAlex. We first performed a bibliometric analysis to examine paper trends, model applications, and collaboration networks. Next, we manually reviewed and categorized each paper into one of the seven identified topics: named entity recognition, information extraction, text similarity, text summarization, text classification, dialogue system, and diagnosis and prediction. For each topic, we discussed the unique capabilities of LLMs, such as their ability to understand context, capture semantic relations, and generate human-like text. Finally, we highlighted several implications for researchers from the perspectives of data resources, prompt engineering, fine-tuning, performance measures, and ethical concerns. In conclusion, this study provides valuable insights into the potential of LLMs to transform EHR research and discusses their applications and ethical considerations.
title A scoping review of using Large Language Models (LLMs) to investigate Electronic Health Records (EHRs)
topic Emerging Technologies
url https://arxiv.org/abs/2405.03066