DALK: Dynamic Co-Augmentation of LLMs and KG to answer Alzheimer's Disease Questions with Scientific Literature

Fuente: arXiv
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Autores principales: Li, Dawei, Yang, Shu, Tan, Zhen, Baik, Jae Young, Yun, Sukwon, Lee, Joseph, Chacko, Aaron, Hou, Bojian, Duong-Tran, Duy, Ding, Ying, Liu, Huan, Shen, Li, Chen, Tianlong
Formato: Preprint
Publicado: 2024
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author Li, Dawei
Yang, Shu
Tan, Zhen
Baik, Jae Young
Yun, Sukwon
Lee, Joseph
Chacko, Aaron
Hou, Bojian
Duong-Tran, Duy
Ding, Ying
Liu, Huan
Shen, Li
Chen, Tianlong
author_facet Li, Dawei
Yang, Shu
Tan, Zhen
Baik, Jae Young
Yun, Sukwon
Lee, Joseph
Chacko, Aaron
Hou, Bojian
Duong-Tran, Duy
Ding, Ying
Liu, Huan
Shen, Li
Chen, Tianlong
contents Recent advancements in large language models (LLMs) have achieved promising performances across various applications. Nonetheless, the ongoing challenge of integrating long-tail knowledge continues to impede the seamless adoption of LLMs in specialized domains. In this work, we introduce DALK, a.k.a. Dynamic Co-Augmentation of LLMs and KG, to address this limitation and demonstrate its ability on studying Alzheimer's Disease (AD), a specialized sub-field in biomedicine and a global health priority. With a synergized framework of LLM and KG mutually enhancing each other, we first leverage LLM to construct an evolving AD-specific knowledge graph (KG) sourced from AD-related scientific literature, and then we utilize a coarse-to-fine sampling method with a novel self-aware knowledge retrieval approach to select appropriate knowledge from the KG to augment LLM inference capabilities. The experimental results, conducted on our constructed AD question answering (ADQA) benchmark, underscore the efficacy of DALK. Additionally, we perform a series of detailed analyses that can offer valuable insights and guidelines for the emerging topic of mutually enhancing KG and LLM. We will release the code and data at https://github.com/David-Li0406/DALK.
format Preprint
id arxiv_https___arxiv_org_abs_2405_04819
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle DALK: Dynamic Co-Augmentation of LLMs and KG to answer Alzheimer's Disease Questions with Scientific Literature
Li, Dawei
Yang, Shu
Tan, Zhen
Baik, Jae Young
Yun, Sukwon
Lee, Joseph
Chacko, Aaron
Hou, Bojian
Duong-Tran, Duy
Ding, Ying
Liu, Huan
Shen, Li
Chen, Tianlong
Computation and Language
Artificial Intelligence
Recent advancements in large language models (LLMs) have achieved promising performances across various applications. Nonetheless, the ongoing challenge of integrating long-tail knowledge continues to impede the seamless adoption of LLMs in specialized domains. In this work, we introduce DALK, a.k.a. Dynamic Co-Augmentation of LLMs and KG, to address this limitation and demonstrate its ability on studying Alzheimer's Disease (AD), a specialized sub-field in biomedicine and a global health priority. With a synergized framework of LLM and KG mutually enhancing each other, we first leverage LLM to construct an evolving AD-specific knowledge graph (KG) sourced from AD-related scientific literature, and then we utilize a coarse-to-fine sampling method with a novel self-aware knowledge retrieval approach to select appropriate knowledge from the KG to augment LLM inference capabilities. The experimental results, conducted on our constructed AD question answering (ADQA) benchmark, underscore the efficacy of DALK. Additionally, we perform a series of detailed analyses that can offer valuable insights and guidelines for the emerging topic of mutually enhancing KG and LLM. We will release the code and data at https://github.com/David-Li0406/DALK.
title DALK: Dynamic Co-Augmentation of LLMs and KG to answer Alzheimer's Disease Questions with Scientific Literature
topic Computation and Language
Artificial Intelligence
url https://arxiv.org/abs/2405.04819