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Auteurs principaux: Moradi, Siyavash, Tomann, Rebecca, Hendrix, Josie, Head-Gordon, Martin, Stein, Christopher J.
Format: Preprint
Publié: 2024
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Accès en ligne:https://arxiv.org/abs/2405.05761
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author Moradi, Siyavash
Tomann, Rebecca
Hendrix, Josie
Head-Gordon, Martin
Stein, Christopher J.
author_facet Moradi, Siyavash
Tomann, Rebecca
Hendrix, Josie
Head-Gordon, Martin
Stein, Christopher J.
contents We present an optimization strategy for atom-specific spin-polarization constants within the spin-polarized GFN2-xTB framework, aiming to enhance the accuracy of molecular simulations. We compare a sequential and global optimization of spin parameters for hydrogen, carbon, nitrogen, oxygen, and fluorine. Sensitivity analysis using Sobol indices guides the identification of the most influential parameters for a given reference dataset, allowing for a nuanced understanding of their impact on diverse molecular properties. In the case of the W4-11 dataset, substantial error reduction was achieved, demonstrating the potential of the optimization. Transferability of the optimized spin-polarization constants over different properties, however, is limited, as we demonstrate by applying the optimized parameters on a set of singlet-triplet gaps in carbenes. Further studies on ionization potentials and electron affinities highlight some inherent limitations of current extended tight-binding methods that can not be resolved by simple parameter optimization. We conclude that the significantly improved accuracy strongly encourages the present re-optimization of the spin-polarization constants, whereas the limited transferability motivates a property-specific optimization strategy.
format Preprint
id arxiv_https___arxiv_org_abs_2405_05761
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Spin parameter optimization for spin-polarized extended tight-binding methods
Moradi, Siyavash
Tomann, Rebecca
Hendrix, Josie
Head-Gordon, Martin
Stein, Christopher J.
Chemical Physics
We present an optimization strategy for atom-specific spin-polarization constants within the spin-polarized GFN2-xTB framework, aiming to enhance the accuracy of molecular simulations. We compare a sequential and global optimization of spin parameters for hydrogen, carbon, nitrogen, oxygen, and fluorine. Sensitivity analysis using Sobol indices guides the identification of the most influential parameters for a given reference dataset, allowing for a nuanced understanding of their impact on diverse molecular properties. In the case of the W4-11 dataset, substantial error reduction was achieved, demonstrating the potential of the optimization. Transferability of the optimized spin-polarization constants over different properties, however, is limited, as we demonstrate by applying the optimized parameters on a set of singlet-triplet gaps in carbenes. Further studies on ionization potentials and electron affinities highlight some inherent limitations of current extended tight-binding methods that can not be resolved by simple parameter optimization. We conclude that the significantly improved accuracy strongly encourages the present re-optimization of the spin-polarization constants, whereas the limited transferability motivates a property-specific optimization strategy.
title Spin parameter optimization for spin-polarized extended tight-binding methods
topic Chemical Physics
url https://arxiv.org/abs/2405.05761