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Auteurs principaux: Durvasula, Maya M., Eyuboglu, Sabri, Ritzwoller, David M.
Format: Preprint
Publié: 2024
Sujets:
Accès en ligne:https://arxiv.org/abs/2405.08030
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author Durvasula, Maya M.
Eyuboglu, Sabri
Ritzwoller, David M.
author_facet Durvasula, Maya M.
Eyuboglu, Sabri
Ritzwoller, David M.
contents We develop a method for assigning high-quality labels to unstructured text. This method is based on fine-tuning an efficient, open-source language model with data extracted from a large, proprietary language model. We apply this method to construct a census of published clinical trials. With these data, we revisit a literature that contends that pharmaceutical sector productivity is declining. Central to this conclusion are measurements of substantial increases in the quantity of clinical trials over time, unmatched by trends in measures of output. In our data, the quantity, quality, and composition of clinical trials are stable since 2010. We show that previous measurements are an artifact of biases introduced by shifts in the composition of other forms of research.
format Preprint
id arxiv_https___arxiv_org_abs_2405_08030
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Counting Clinical Trials: New Evidence on Pharmaceutical Sector Productivity
Durvasula, Maya M.
Eyuboglu, Sabri
Ritzwoller, David M.
General Economics
Economics
We develop a method for assigning high-quality labels to unstructured text. This method is based on fine-tuning an efficient, open-source language model with data extracted from a large, proprietary language model. We apply this method to construct a census of published clinical trials. With these data, we revisit a literature that contends that pharmaceutical sector productivity is declining. Central to this conclusion are measurements of substantial increases in the quantity of clinical trials over time, unmatched by trends in measures of output. In our data, the quantity, quality, and composition of clinical trials are stable since 2010. We show that previous measurements are an artifact of biases introduced by shifts in the composition of other forms of research.
title Counting Clinical Trials: New Evidence on Pharmaceutical Sector Productivity
topic General Economics
Economics
url https://arxiv.org/abs/2405.08030