Synchronization of E. coli bacteria moving in coupled wells
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arXiv
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| Main Authors: | , , , , , , |
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| Format: | Preprint |
| Published: |
2024
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| _version_ | 1866929343860572160 |
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| author | Japaridze, Aleksandre Struijk, Victor Swamy, Kushal Roslon, Irek Shoshani, Oriel Dekker, Cees Alijani, Farbod |
| author_facet | Japaridze, Aleksandre Struijk, Victor Swamy, Kushal Roslon, Irek Shoshani, Oriel Dekker, Cees Alijani, Farbod |
| contents | Synchronization plays a crucial role in the dynamics of living organisms, from fireflies flashing in unison to pacemaker cells that jointly generate heartbeats. Uncovering the mechanism behind these phenomena requires an understanding of individual biological oscillators and the coupling forces between them. Here, we develop a single-cell assay that studies rhythmic behavior in the motility of individual E.coli cells that can be mutually synchronized. Circular microcavities are used to isolate E.coli cells that swim along the cavity wall, resulting in self-sustained oscillations. Upon connecting these cavities by microchannels the bacterial motions can be coupled, yielding nonlinear dynamic synchronization patterns with phase slips. We demonstrate that the coordinated movement observed in coupled E. coli oscillators follows mathematical rules of synchronization which we use to quantify the coupling strength. These findings advance our understanding of motility in confinement, and lay the foundation for engineering desired dynamics in microbial active matter. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2405_09147 |
| institution | arXiv |
| publishDate | 2024 |
| record_format | arxiv |
| spellingShingle | Synchronization of E. coli bacteria moving in coupled wells Japaridze, Aleksandre Struijk, Victor Swamy, Kushal Roslon, Irek Shoshani, Oriel Dekker, Cees Alijani, Farbod Adaptation and Self-Organizing Systems Other Condensed Matter Biological Physics Synchronization plays a crucial role in the dynamics of living organisms, from fireflies flashing in unison to pacemaker cells that jointly generate heartbeats. Uncovering the mechanism behind these phenomena requires an understanding of individual biological oscillators and the coupling forces between them. Here, we develop a single-cell assay that studies rhythmic behavior in the motility of individual E.coli cells that can be mutually synchronized. Circular microcavities are used to isolate E.coli cells that swim along the cavity wall, resulting in self-sustained oscillations. Upon connecting these cavities by microchannels the bacterial motions can be coupled, yielding nonlinear dynamic synchronization patterns with phase slips. We demonstrate that the coordinated movement observed in coupled E. coli oscillators follows mathematical rules of synchronization which we use to quantify the coupling strength. These findings advance our understanding of motility in confinement, and lay the foundation for engineering desired dynamics in microbial active matter. |
| title | Synchronization of E. coli bacteria moving in coupled wells |
| topic | Adaptation and Self-Organizing Systems Other Condensed Matter Biological Physics |
| url | https://arxiv.org/abs/2405.09147 |