MMFusion: Multi-modality Diffusion Model for Lymph Node Metastasis Diagnosis in Esophageal Cancer

Fuente: arXiv
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Main Authors: Wu, Chengyu, Wang, Chengkai, Wang, Yaqi, Zhou, Huiyu, Zhang, Yatao, Wang, Qifeng, Wang, Shuai
Format: Preprint
Published: 2024
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author Wu, Chengyu
Wang, Chengkai
Wang, Yaqi
Zhou, Huiyu
Zhang, Yatao
Wang, Qifeng
Wang, Shuai
author_facet Wu, Chengyu
Wang, Chengkai
Wang, Yaqi
Zhou, Huiyu
Zhang, Yatao
Wang, Qifeng
Wang, Shuai
contents Esophageal cancer is one of the most common types of cancer worldwide and ranks sixth in cancer-related mortality. Accurate computer-assisted diagnosis of cancer progression can help physicians effectively customize personalized treatment plans. Currently, CT-based cancer diagnosis methods have received much attention for their comprehensive ability to examine patients' conditions. However, multi-modal based methods may likely introduce information redundancy, leading to underperformance. In addition, efficient and effective interactions between multi-modal representations need to be further explored, lacking insightful exploration of prognostic correlation in multi-modality features. In this work, we introduce a multi-modal heterogeneous graph-based conditional feature-guided diffusion model for lymph node metastasis diagnosis based on CT images as well as clinical measurements and radiomics data. To explore the intricate relationships between multi-modal features, we construct a heterogeneous graph. Following this, a conditional feature-guided diffusion approach is applied to eliminate information redundancy. Moreover, we propose a masked relational representation learning strategy, aiming to uncover the latent prognostic correlations and priorities of primary tumor and lymph node image representations. Various experimental results validate the effectiveness of our proposed method. The code is available at https://github.com/wuchengyu123/MMFusion.
format Preprint
id arxiv_https___arxiv_org_abs_2405_09539
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle MMFusion: Multi-modality Diffusion Model for Lymph Node Metastasis Diagnosis in Esophageal Cancer
Wu, Chengyu
Wang, Chengkai
Wang, Yaqi
Zhou, Huiyu
Zhang, Yatao
Wang, Qifeng
Wang, Shuai
Image and Video Processing
Computer Vision and Pattern Recognition
Multimedia
Esophageal cancer is one of the most common types of cancer worldwide and ranks sixth in cancer-related mortality. Accurate computer-assisted diagnosis of cancer progression can help physicians effectively customize personalized treatment plans. Currently, CT-based cancer diagnosis methods have received much attention for their comprehensive ability to examine patients' conditions. However, multi-modal based methods may likely introduce information redundancy, leading to underperformance. In addition, efficient and effective interactions between multi-modal representations need to be further explored, lacking insightful exploration of prognostic correlation in multi-modality features. In this work, we introduce a multi-modal heterogeneous graph-based conditional feature-guided diffusion model for lymph node metastasis diagnosis based on CT images as well as clinical measurements and radiomics data. To explore the intricate relationships between multi-modal features, we construct a heterogeneous graph. Following this, a conditional feature-guided diffusion approach is applied to eliminate information redundancy. Moreover, we propose a masked relational representation learning strategy, aiming to uncover the latent prognostic correlations and priorities of primary tumor and lymph node image representations. Various experimental results validate the effectiveness of our proposed method. The code is available at https://github.com/wuchengyu123/MMFusion.
title MMFusion: Multi-modality Diffusion Model for Lymph Node Metastasis Diagnosis in Esophageal Cancer
topic Image and Video Processing
Computer Vision and Pattern Recognition
Multimedia
url https://arxiv.org/abs/2405.09539