Seasonality and susceptibility from measles time series

Fuente: arXiv
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Main Authors: Thakkar, Niket, Jindal, Sonia, Rosenfeld, Katherine
Format: Preprint
Published: 2024
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author Thakkar, Niket
Jindal, Sonia
Rosenfeld, Katherine
author_facet Thakkar, Niket
Jindal, Sonia
Rosenfeld, Katherine
contents This paper develops mathematical tools to estimate seasonal changes in measles transmission rates and corresponding variation in population susceptibility. The tools are designed to leverage times series of cases in the absence of demographic data. In particular, we focus on publicly available suspected case reports from the World Health Organization (WHO), which routinely publishes country-level, monthly aggregated time series. With that as input, we show that measles epidemiologies can be characterized efficiently at global-scale, and we use our estimates to recommend context-specific, future supplementary immunization times. Throughout the paper, comparisons with more data-informed models illustrate that the approach captures the essential dynamics, and broadly speaking, the tools we describe represent a scalable intermediate between conventional empirical approaches and more intricate disease models.
format Preprint
id arxiv_https___arxiv_org_abs_2405_09664
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Seasonality and susceptibility from measles time series
Thakkar, Niket
Jindal, Sonia
Rosenfeld, Katherine
Populations and Evolution
This paper develops mathematical tools to estimate seasonal changes in measles transmission rates and corresponding variation in population susceptibility. The tools are designed to leverage times series of cases in the absence of demographic data. In particular, we focus on publicly available suspected case reports from the World Health Organization (WHO), which routinely publishes country-level, monthly aggregated time series. With that as input, we show that measles epidemiologies can be characterized efficiently at global-scale, and we use our estimates to recommend context-specific, future supplementary immunization times. Throughout the paper, comparisons with more data-informed models illustrate that the approach captures the essential dynamics, and broadly speaking, the tools we describe represent a scalable intermediate between conventional empirical approaches and more intricate disease models.
title Seasonality and susceptibility from measles time series
topic Populations and Evolution
url https://arxiv.org/abs/2405.09664