Paired Conditional Generative Adversarial Network for Highly Accelerated Liver 4D MRI

Fuente: arXiv
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Main Authors: Xu, Di, Miao, Xin, Liu, Hengjie, Scholey, Jessica E., Yang, Wensha, Feng, Mary, Ohliger, Michael, Lin, Hui, Lao, Yi, Yang, Yang, Sheng, Ke
Format: Preprint
Published: 2024
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author Xu, Di
Miao, Xin
Liu, Hengjie
Scholey, Jessica E.
Yang, Wensha
Feng, Mary
Ohliger, Michael
Lin, Hui
Lao, Yi
Yang, Yang
Sheng, Ke
author_facet Xu, Di
Miao, Xin
Liu, Hengjie
Scholey, Jessica E.
Yang, Wensha
Feng, Mary
Ohliger, Michael
Lin, Hui
Lao, Yi
Yang, Yang
Sheng, Ke
contents Purpose: 4D MRI with high spatiotemporal resolution is desired for image-guided liver radiotherapy. Acquiring densely sampling k-space data is time-consuming. Accelerated acquisition with sparse samples is desirable but often causes degraded image quality or long reconstruction time. We propose the Reconstruct Paired Conditional Generative Adversarial Network (Re-Con-GAN) to shorten the 4D MRI reconstruction time while maintaining the reconstruction quality. Methods: Patients who underwent free-breathing liver 4D MRI were included in the study. Fully- and retrospectively under-sampled data at 3, 6 and 10 times (3x, 6x and 10x) were first reconstructed using the nuFFT algorithm. Re-Con-GAN then trained input and output in pairs. Three types of networks, ResNet9, UNet and reconstruction swin transformer, were explored as generators. PatchGAN was selected as the discriminator. Re-Con-GAN processed the data (3D+t) as temporal slices (2D+t). A total of 48 patients with 12332 temporal slices were split into training (37 patients with 10721 slices) and test (11 patients with 1611 slices). Results: Re-Con-GAN consistently achieved comparable/better PSNR, SSIM, and RMSE scores compared to CS/UNet models. The inference time of Re-Con-GAN, UNet and CS are 0.15s, 0.16s, and 120s. The GTV detection task showed that Re-Con-GAN and CS, compared to UNet, better improved the dice score (3x Re-Con-GAN 80.98%; 3x CS 80.74%; 3x UNet 79.88%) of unprocessed under-sampled images (3x 69.61%). Conclusion: A generative network with adversarial training is proposed with promising and efficient reconstruction results demonstrated on an in-house dataset. The rapid and qualitative reconstruction of 4D liver MR has the potential to facilitate online adaptive MR-guided radiotherapy for liver cancer.
format Preprint
id arxiv_https___arxiv_org_abs_2405_12357
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Paired Conditional Generative Adversarial Network for Highly Accelerated Liver 4D MRI
Xu, Di
Miao, Xin
Liu, Hengjie
Scholey, Jessica E.
Yang, Wensha
Feng, Mary
Ohliger, Michael
Lin, Hui
Lao, Yi
Yang, Yang
Sheng, Ke
Image and Video Processing
Computer Vision and Pattern Recognition
Purpose: 4D MRI with high spatiotemporal resolution is desired for image-guided liver radiotherapy. Acquiring densely sampling k-space data is time-consuming. Accelerated acquisition with sparse samples is desirable but often causes degraded image quality or long reconstruction time. We propose the Reconstruct Paired Conditional Generative Adversarial Network (Re-Con-GAN) to shorten the 4D MRI reconstruction time while maintaining the reconstruction quality. Methods: Patients who underwent free-breathing liver 4D MRI were included in the study. Fully- and retrospectively under-sampled data at 3, 6 and 10 times (3x, 6x and 10x) were first reconstructed using the nuFFT algorithm. Re-Con-GAN then trained input and output in pairs. Three types of networks, ResNet9, UNet and reconstruction swin transformer, were explored as generators. PatchGAN was selected as the discriminator. Re-Con-GAN processed the data (3D+t) as temporal slices (2D+t). A total of 48 patients with 12332 temporal slices were split into training (37 patients with 10721 slices) and test (11 patients with 1611 slices). Results: Re-Con-GAN consistently achieved comparable/better PSNR, SSIM, and RMSE scores compared to CS/UNet models. The inference time of Re-Con-GAN, UNet and CS are 0.15s, 0.16s, and 120s. The GTV detection task showed that Re-Con-GAN and CS, compared to UNet, better improved the dice score (3x Re-Con-GAN 80.98%; 3x CS 80.74%; 3x UNet 79.88%) of unprocessed under-sampled images (3x 69.61%). Conclusion: A generative network with adversarial training is proposed with promising and efficient reconstruction results demonstrated on an in-house dataset. The rapid and qualitative reconstruction of 4D liver MR has the potential to facilitate online adaptive MR-guided radiotherapy for liver cancer.
title Paired Conditional Generative Adversarial Network for Highly Accelerated Liver 4D MRI
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2405.12357