Hybrid PDE-ODE Models for Efficient Simulation of Infection Spread in Epidemiology

Fuente: arXiv
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Main Authors: Kehrer, Kristina, Weiser, Martin, Conrad, Tim
Format: Preprint
Published: 2024
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author Kehrer, Kristina
Weiser, Martin
Conrad, Tim
author_facet Kehrer, Kristina
Weiser, Martin
Conrad, Tim
contents This paper introduces a novel hybrid model combining Partial Differential Equations (PDEs) and Ordinary Differential Equations (ODEs) to simulate infectious disease dynamics across geographic regions. By leveraging the spatial detail of PDEs and the computational efficiency of ODEs, the model enables rapid evaluation of public health interventions. Applied to synthetic environments and real-world scenarios in Lombardy, Italy, and Berlin, Germany, the model highlights how interactions between PDE and ODE regions affect infection dynamics, especially in high-density areas. Key findings reveal that the placement of model boundaries in densely populated regions can lead to inaccuracies in infection spread, suggesting that boundaries should be positioned in areas of lower population density to better reflect transmission dynamics. Additionally, regions with low population density hinder infection flow, indicating a need for incorporating, e.g., jumps in the model to enhance its predictive capabilities. Results indicate that the hybrid model achieves a balance between computational speed and accuracy, making it a valuable tool for policymakers in real-time decision-making and scenario analysis in epidemiology and potentially in other fields requiring similar modeling approaches.
format Preprint
id arxiv_https___arxiv_org_abs_2405_12938
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle Hybrid PDE-ODE Models for Efficient Simulation of Infection Spread in Epidemiology
Kehrer, Kristina
Weiser, Martin
Conrad, Tim
Dynamical Systems
This paper introduces a novel hybrid model combining Partial Differential Equations (PDEs) and Ordinary Differential Equations (ODEs) to simulate infectious disease dynamics across geographic regions. By leveraging the spatial detail of PDEs and the computational efficiency of ODEs, the model enables rapid evaluation of public health interventions. Applied to synthetic environments and real-world scenarios in Lombardy, Italy, and Berlin, Germany, the model highlights how interactions between PDE and ODE regions affect infection dynamics, especially in high-density areas. Key findings reveal that the placement of model boundaries in densely populated regions can lead to inaccuracies in infection spread, suggesting that boundaries should be positioned in areas of lower population density to better reflect transmission dynamics. Additionally, regions with low population density hinder infection flow, indicating a need for incorporating, e.g., jumps in the model to enhance its predictive capabilities. Results indicate that the hybrid model achieves a balance between computational speed and accuracy, making it a valuable tool for policymakers in real-time decision-making and scenario analysis in epidemiology and potentially in other fields requiring similar modeling approaches.
title Hybrid PDE-ODE Models for Efficient Simulation of Infection Spread in Epidemiology
topic Dynamical Systems
url https://arxiv.org/abs/2405.12938