Maximum Caliber Infers Effective Coupling and Response from Spiking Networks

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Auteurs principaux:	Chen, Kevin S., Yang, Ying-Jen
Format:	Preprint
Publié:	2024
Sujets:	Neurons and Cognition Biological Physics
Accès en ligne:	Acceder al recurso
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_version_	1866916258988949504
author	Chen, Kevin S. Yang, Ying-Jen
author_facet	Chen, Kevin S. Yang, Ying-Jen
contents	The characterization of network and biophysical properties from neural spiking activity is an important goal in neuroscience. A framework that provides unbiased inference on causal synaptic interaction and single neural properties has been missing. Here we applied the stochastic dynamics extension of Maximum Entropy -- the Maximum Caliber Principle -- to infer the transition rates of network states. Effective synaptic coupling strength and neuronal response functions for various network motifs can then be computed. The inferred minimal model also enables leading-order reconstruction of inter-spike interval distribution. Our method is tested with numerical simulated spiking networks and applied to data from salamander retina.
format	Preprint
id	arxiv_https___arxiv_org_abs_2405_15206
institution	arXiv
publishDate	2024
record_format	arxiv
spellingShingle	Maximum Caliber Infers Effective Coupling and Response from Spiking Networks Chen, Kevin S. Yang, Ying-Jen Neurons and Cognition Biological Physics The characterization of network and biophysical properties from neural spiking activity is an important goal in neuroscience. A framework that provides unbiased inference on causal synaptic interaction and single neural properties has been missing. Here we applied the stochastic dynamics extension of Maximum Entropy -- the Maximum Caliber Principle -- to infer the transition rates of network states. Effective synaptic coupling strength and neuronal response functions for various network motifs can then be computed. The inferred minimal model also enables leading-order reconstruction of inter-spike interval distribution. Our method is tested with numerical simulated spiking networks and applied to data from salamander retina.
title	Maximum Caliber Infers Effective Coupling and Response from Spiking Networks
topic	Neurons and Cognition Biological Physics
url	https://arxiv.org/abs/2405.15206

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