SiNGR: Brain Tumor Segmentation via Signed Normalized Geodesic Transform Regression

Fuente: arXiv
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Autores principales: Dang, Trung, Nguyen, Huy Hoang, Tiulpin, Aleksei
Formato: Preprint
Publicado: 2024
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author Dang, Trung
Nguyen, Huy Hoang
Tiulpin, Aleksei
author_facet Dang, Trung
Nguyen, Huy Hoang
Tiulpin, Aleksei
contents One of the primary challenges in brain tumor segmentation arises from the uncertainty of voxels close to tumor boundaries. However, the conventional process of generating ground truth segmentation masks fails to treat such uncertainties properly. Those "hard labels" with 0s and 1s conceptually influenced the majority of prior studies on brain image segmentation. As a result, tumor segmentation is often solved through voxel classification. In this work, we instead view this problem as a voxel-level regression, where the ground truth represents a certainty mapping from any pixel to the border of the tumor. We propose a novel ground truth label transformation, which is based on a signed geodesic transform, to capture the uncertainty in brain tumors' vicinity. We combine this idea with a Focal-like regression L1-loss that enables effective regression learning in high-dimensional output space by appropriately weighting voxels according to their difficulty. We thoroughly conduct an experimental evaluation to validate the components of our proposed method, compare it to a diverse array of state-of-the-art segmentation models, and show that it is architecture-agnostic. The code of our method is made publicly available (\url{https://github.com/Oulu-IMEDS/SiNGR/}).
format Preprint
id arxiv_https___arxiv_org_abs_2405_16813
institution arXiv
publishDate 2024
record_format arxiv
spellingShingle SiNGR: Brain Tumor Segmentation via Signed Normalized Geodesic Transform Regression
Dang, Trung
Nguyen, Huy Hoang
Tiulpin, Aleksei
Computer Vision and Pattern Recognition
One of the primary challenges in brain tumor segmentation arises from the uncertainty of voxels close to tumor boundaries. However, the conventional process of generating ground truth segmentation masks fails to treat such uncertainties properly. Those "hard labels" with 0s and 1s conceptually influenced the majority of prior studies on brain image segmentation. As a result, tumor segmentation is often solved through voxel classification. In this work, we instead view this problem as a voxel-level regression, where the ground truth represents a certainty mapping from any pixel to the border of the tumor. We propose a novel ground truth label transformation, which is based on a signed geodesic transform, to capture the uncertainty in brain tumors' vicinity. We combine this idea with a Focal-like regression L1-loss that enables effective regression learning in high-dimensional output space by appropriately weighting voxels according to their difficulty. We thoroughly conduct an experimental evaluation to validate the components of our proposed method, compare it to a diverse array of state-of-the-art segmentation models, and show that it is architecture-agnostic. The code of our method is made publicly available (\url{https://github.com/Oulu-IMEDS/SiNGR/}).
title SiNGR: Brain Tumor Segmentation via Signed Normalized Geodesic Transform Regression
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2405.16813